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Explore Genetech’s lab facilities, equipment, and expertise for your research. Access GRI’s support services, including sample storage and international shipment coordination. GRI Research Policies for External Researchers Genetech offers scientific expertise, technical services and laboratory facilities for research projects. External researchers will have access to all the following services: Bench space and access to all equipment at GRI Scientific and technical expertise of GRI permanent staff Common chemicals and supplies Assistance in ordering and receiving research supplies Library, computer and internet facilities at GRI Short term sample storage at 4 C, -20 C and -80 C. Coordination of international shipment of specimen (subject to local and international export/import regulations) Above services can be obtained under following broad categories, with the flexibility to accommodate the individual researcher's requirements.

Discover Genetech’s DNA testing accuracy for identity, parentage, and forensics, ensuring over 99.99% paternity certainty and match probabilities beyond standards. Accuracy of evidence DNA testing is the most accurate and reliable means of identity verification and parentage testing. The degree of accuracy of the test will depend on the genetic diversity of the Sri Lankan population as well as the number of genetic locations (STR loci) which are tested. There is no mandatory number of STR loci required for a test, but the testing of nine STR loci or more is generally considered to be sufficiently accurate. We test up to 15 STR loci. Accuracy in a test of familial relationships: A paternity or maternity test can prove with 100% certainty that an individual is not the biological parent of a child. However, no DNA test available can prove with 100% certainty that a man or woman is the biological parent of a child. Generally, a degree of certainty of over 99% is required to accept the paternity or maternity of an individual. DNA testing by Genetech typically proves paternity with at least 99.99% certainty. This is well in excess of the required accuracy. Accuracy in criminal casework: In criminal casework, the demand for accuracy is greater, and the forensic scientist has to prove beyond a doubt that a suspect's DNA profile matches with that of the criminal. This involves expressing the probability of finding a random person in the population who might have this same profile. This probability is known as the Match Probability. This probability must be very low. When the Match Probability is lower, the accuracy of the conclusions of the DNA test is greater. There is no internationally agreed lower limit for this probability, but the result is generally accepted if it is lower than 1 in 1 billion. At Genetech, a sufficient number of loci can be tested to ensure that the Match Probability is lower than 1 in 10 billion.

Master PCR Technology in this 18-hour course. Ideal for students and professionals, covering PCR principles, applications, and hands-on practicals like DNA extraction, PCR assays, and troubleshooting. Polymerase Chain Reaction (PCR) Technology (18 hours) This course is suitable for school-level, undergraduate and graduate students, and those engaged in scientific research, diagnostics and teaching which involves Polymerase Chain Reaction (PCR) Technology. Theory: Guidelines for PCR Principle of PCR Critical factors for successful PCR Designing PCR primers Standard practices in a PCR Laboratory Troubleshooting and prevention of carryover contamination Optimization strategies for PCR PCR product analysis: Detection of PCR products by gel electrophoresis Methods of purification and quantification of PCR products Methods of labelling of PCR products (PCR probes) and visualization of label Cloning of PCR products: TOPO cloning DNA sequence analysis of PCR product PCR Applications: Restriction Fragment Length Polymorphism (RFLP) and Randomly Amplified Polymorphic DNA (RAPD) analysis Short Tandem Repeat (STR) (micro-satellite) analysis Multiplex PCR Reverse Transcription (RT)-PCR PCR-ELISA (Enzyme Linked Immunosorbent Assay) In-situ PCR Quality Control/Quality Assurance of PCR assays Practicals: Extraction of DNA from cells, blood stains for PCR A standard PCR assay Analysis of PCR products by agarose and acrylamide gel electrophoresis Strategies for optimization of PCR Purification of PCR products Labelling of PCR products Primer design using online sequence databases PCR-RFLP assay Multiplex PCR assay RT-PCR assay PCR-ELISA assay PCR troubleshooting View FAQs Contact us If you are interested in doing this course at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form

Discover Genetech’s innovative DNA/RNA extraction and PCR amplification kits, tailored for research and industrial needs. Click to explore our customizable solutions! Product Development Our research projects often aim for a final product which can range from developing a new diagnostic test to a commercial nucleic acid extraction or amplification kit. Research and development projects have given rise to Genetech's new product line. DNA and RNA extraction kits We have developed a wide range of DNA/RNA extraction kits such as viral RNA/DNA extraction kits, Bacterial genomic and plasmid DNA extraction kits, plant DNA extraction kits, human and other animal genomic DNA extraction kits. The kits are starting from 25 prep size and are scaled up to 100s to meet the wide array of requirements found in the research community. For optimum results, we also provide customised extraction kits for low yielding starting materials like insect and bone samples. PCR amplification kits We offer customised conventional and real time PCR amplification kits (Ready mix PCR kits) for both DNA and RNA. This can be integrated with primer designing and PCR optimisation as required for the best results. Industrially important kits We offer to develop industrially important test kits to meet specific needs. For example, White Spot Syndrome Virus Detection Kit for shrimps was developed for the shrimp farm industry, based on customer requirements. You can contact us to discuss your specific requirement. We are able to design and develop customised kits for a wide variety of industrial needs. Contact us

Explore diverse research on genetic variation, virological surveillance, and forensic DNA evidence in Sri Lanka, presented at various academic conferences and symposiums. Conference Papers and Communications Page 2 of 2 De Silva, A. D., Perera, N., Abeysekera, D. M. & Elvitigala, J. P. (2009) Molecular characterization of Mycobacterium tuberculosis(MTB) isolates in Sri Lanka utilizing the Mycobaterium interspersed repetitive units(MIRU) typing method. Respire, Inaugural symposium of the association of pulmonologists. De Silva, A. D., Samarasinghe, K. S. R. G. S. L., Abeysekera, D. M. & Elvitigala, J. P. (2009) Screening for IS6110 zero copy number strains of Mycobacterium tuberculosis in Sri Lanka Genetech Research Institute, Colombo 8, Chest Hospital, Welisara. The Bulletin of the Sri Lanka College of Microbiologists, volume 7, Issue 1. Muthunayake, T., Dangalle, C., Fernandopulle, N. & Weerakoon, D. (2009) Genetic analysis of morphologically non-identifiable translocated Puntius bandula population at Salgala using CO1 region of mt DNA. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 66. Available from: https://www.researchgate.net/publication/335926117_Genetic_analysis_of_morphologically_non-identifiable_translocated_Puntius_bandula_population_at_Salgala_using_CO1_region_of_mtDNA Wickramasinghe, E. D. T. S. L., Fernandopulle, N. D. & Hettiarachchi, P. L. L. (2009) DNA barcoding of Sri Lankan Tea - A method to secure ownership in the international trade. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 68. Samaradivakara, S., Gunasekera, I., Mendis, B., Karunaratne, U., Jayathunga, T., Sledgers, R. & Fernandopulle, N. (2009) Preliminary study on DNA barcoding of cinnamon varieties in Sri Lanka. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 69-70. Fernando, A., Samaradivakara, S., De Silva, A. D., Baranage, G., Herath, I., Fernandopulle, N. D., Padmalal, K. & Ranawaka, G. R. R. (2009) DNA Barcoding of the Sri Lankan Slender Loris (Loris tardigradus or Loris lydekkerianus?) A preliminary report. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 74. Available from: http://repository.ou.ac.lk/handle/94ousl/1845 Rajasinghe, M. H. L. D., Fernandopulle, N. & Perera, A. L. T. (2009) Detection of Genetically Modified Soy Food in Sri Lankan Supermarket, Paper Presented at the Proceedings of the Peradeniya, University Research Sessions, University of Peradeniya, Peradeniya, Sri Lanka.Vol:14 (1) pp: 16-18. Perera, A. N. K., Logendra, B., Fernandopulle, N. D. & Attanayaka, D. P. S. T. G. (2009) Development of a PCR-based molecular Detection Assay for Thielaviopsis paradoxa in Coconut Fibre Dust. Proceedings of 9th Agricultural Research Symposium, Wayamba University of Sri Lanka. 326-331. Tissera, H. A., De Silva, A. D., Abeysinghe, M. R. N., de Silva, A. M., Palihawadana, P., Gunasena, S., Tam, C. C., Gamage, T. M., De Silva, T., Rajapaksa, L. C., Amarasinghe, A., Letson, G. W. & Margolis, H. S. (2009) Dengue Surveillance in Colombo, Sri Lanka: Baseline seroprevalence among children. Procedia in Vaccinology . 2(1) 110–114. Available from: doi: 10.1016/j.provac.2010.03.020 Gunathilaka, P. V. V. W., Fernandopulle, N. D. & Attanayaka, D. P. S. T. G. (2007) Development of an in-house method for purification and characterization of Taq DNA polymerase. Proceedings of 7th Agricultural Research Symposium, Wayamba University of Sri Lanka. 1 (1), 27-31. Fernandopulle, N. D. (2007) DNA typing for forensic and civil casework in Sri Lanka; a critical review. Proceedings of the 9th Indo-Pacific Congress on Legal Medicine & Forensic Sciences. Illeperuma, R. J. (2007) Y-Chromosome and Mitochondrial DNA reference data bases for Sri Lankan Human Population, 9th Indo-Pacific Congress on Legal Medicine & Forensic Sciences. OP-72 p83. Markalanda, D. A., Illeperuma, R. J. & Fernandopulle, N. D. (2007) Establishment of a Differential extraction of Male and Female DNA from sexual assault samples - 9th Indo-Pacific Congress on Legal Medicine & Forensic Sciences. Fernandopulle, D. N., Senevirathna, D. B., Ranaweera, D. M., Abeysekara, D., Perera, N., Kanakaratne, N., Jayasinghe, S., Samaraweera, P. & De Silva, A. (2007) Detection of HCV Genotypes among Sri Lankan Patients by Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR). The Bulletin of the Sri Lanka College of Microbiologists Vol 5. Seneviratne, D. & Gunasekera, M. B. (2006) Development of a low-cost in-house RT-PCR assay for the detection of hepatitis C virus. Annual Sessions of the Post Graduate Institute of Science, University of Peradeniya, Sri Lanka. Abbas, R., Senevirathne, D., Ranaweera, D. & Fernandopulle, N. D. (2006) DNA-based detection of Herpes Simplex virus 1 and 2 in clinical samples and its usefulness as a screening test for viral encephalitis. Proceedings of the 62nd Annual Sessions of the Sri Lanka Association for the Advancement of Science. Wahala, M., Messer, W., Kanakaratne, N., Perera, N., Seneviratne, D., Ranawake, G. R., Shahani, A., Ruberu, D., Gunasekera, M. B. & De Silva, A. M. (2005) Virological parameters of recent dengue hemorrhagic fever outbreak in Sri Lanka. Annual sessions of PUBMED, National institutes of Health, USA. Seneviratne, D., Gamage, P., Baranage, G., Jayasinghe, S., Shahani, A., Somaiah, S., Fernandopulle, N. D. & Gunasekera, M. B. (2004). Screening for Hepatitis C virus (HCV) infection by an in-house reverse transcription polymerase chain reaction (RT-PCR) based assay (2004) The Bulletin of the Sri Lanka College of Microbiologists Vol 2 (1). Fernandopulle, N. D., De Silva, V., Perera, N., Jayathilake, M. M., Pieris, D., Balawardana, J., Perera, M. & Gunasekera, M. B. (2004) Screening for Philadelphia Chromosome by an in-house Reverse Transcription-Polymerase Chain Reaction (RT-PCR) based assay. Proceedings of the 60th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Illeperuma, R. J., Fernandopulle, N. D., Senevirathna, D., Baranage, G., Perera, N. & Gunasekera, M. B. (2004). A comparison of theoretical and observed statistical data in paternity testing by DNA analysis. Proceedings of the 60th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Jayathilaka, S., Weerasinghe, R. & Fernandopulle, N. (2004) Predicting ethnic origin from DNA by neural networks. Proceedings of the 6th International Information Technology Conference IITC 2004, Colombo, Sri Lanka. Baranage, G., Seneviratne, D., Gamage, P., Ranawaka, G., Perera, N., Illeperuma, R., Ruberu, D., Shahani, A. & Gunasekera, M. B. (2004) Screening of febrile cases for early diagnosis of dengue and identification of dengue virus type using in-house diagnostic kits based on polymerase chain reaction. The Bulletin of the Sri Lanka College of Microbiologists Vol 2 (1). Illeperuma, R. J., Fernandopulle, N. D., Senevirathna, D., Baranage, G., Perera, N. & Gunasekera, M. B. (2004) DNA-based testing as a social phenomenon in Sri Lanka. Proceedings of the 60th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Ranawaka, G. R., Gamage, P., De Silva, V., Fernando, A., Seneviratne, D. & Gunasekera, M. B. (2003) Evaluation of a polymerase chain reaction (PCR)-agarose gel electrophoresis assay with a PCR-hybridization assay for the detection of Mycobacterium tuberculosis. Proceedings of the 59th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Gamage, P., Seneviratne, D., Herath, C. A., Fernandopulle, N. D. & Gunasekera, M. B. (2003) Polymerase chain reaction based detection of cytomegalovirus infection in Sri Lanka. Proceedings of the 59th Annual Sessions of the Sri Lanka Association for the Advancement of Science. 1 2

Explore Genetech’s inclusive recruitment process: submit your CV, attend interviews with our scientists and CEO, and join our team if selected. Apply now to advance your career! Application Process 01 CV Submission Send us your CV to info@genetechsrilanka.com if you believe your profile matches our requirements for a job advertised on our website. Please make sure you meet the essential requirements before applying for any role. 02 First Interview If we find your CV impressive and your profile meets our requirements after reviewing, we will invite you to an interview with our senior scientists/recruitment team to further assess your skills and get to know you more. The majority of the interview will be strength based, and you can view our top interview tips to help prepare yourself. We are committed to ensuring that our recruitment practices are barrier-free, and as inclusive as possible for everyone. This includes making adjustments for people who require them to perform to the best of their ability. 03 Final Interview If we find your performance at the first interview great and better than most candidates who applied for the same position, we will invite you to the final stage of our recruitment process – an interview with our CEO. 04 Offer Finally, the best candidate(s) will be invited to join our team at Genetech.

Explore custom oligonucleotide and gene synthesis services with various modifications, purification options, free cloning, and sequencing for 100% accuracy. Oligonucleotide and Gene synthesis We offer primer synthesis services covering different concentration scales from 0.025 to 1µmole. Different purification options using techniques such as desalt, MOPC, HPLC and PAGE are available as per requirement of the customer. We also offer primer modifications such as fluorescent labelling, non-fluorescent modifications, dark quenchers and internal modifications. Oligonucleotide/Primer synthesis Gene synthesis We offer customised gene synthesis services in a plasmid DNA state with a free cloning service, as well as free DNA sequencing to confirm the sequence of the gene. Our customised gene synthesis service offers to generate genes based on the sequence requirement of the customer. With our free cloning service, the synthesised gene is made available in a plasmid DNA state. Our free sequencing service guarantees 100% sequence accuracy. Contact us

Discover Genetech’s journal publications on genetic research and advancements in Sri Lanka, shaping the future of molecular diagnostics and biodiversity. Perera, N., Galhena, G. & Ranawaka, G. (2021) X-chromosomal STR based genetic polymorphisms and demographic history of Sri Lankan ethnicities and their relationship with global populations. Scientific Reports 11:12748. Available from: doi: 10.1038/s41598-021-92314-9 Perera, N., Galhena, G. & Ranawaka, G. (2021) Development of a 16 X-STR multiplex PCR system for kinship analysis and its applicability for the Sinhalese population in Sri Lanka. International Journal of Legal Medicine. 135:161–166. Available from: doi: 10.1007/s00414-020-02450-6 Nirmani, M. D., Perera, N. S. & Galhena, G. H. (2021) Population genetic dynamics of dengue vectors Aedes aegypti and Aedes albopictus in Sri Lanka: Baseline study for designing Wolbachia control method. International Journal of Tropical Insect Science. 41:1809–1821. Available from: doi: 10.1007/s42690-020-00395-2 Jayasinghearachchi, H. S., Francis, V. R., Sathkumara, H. D., Krishnananthasivam, S., Masakorala, J., Muthugama, T., De Silva, A. D. & Corea, E. M. (2021) Nonclonal Burkholderia pseudomallei Population in Melioidosis Case Cluster, Sri Lanka. Emerging Infectious Diseases. 27 (11). Available from: doi: 10.3201/eid2711.210219 Nirmani, M. D., Perera, N. S. & Galhena, G. H. (2020) The scope of Rp EPIC markers in population genetic studies: a preliminary study with dengue vectors. Journal of the National Science Foundation of Sri Lanka, 48(3): 275-288. Available from: doi: 10.4038/jnsfsr.v48i3.9311 Dharmarathne, H. A. K. M., Weerasena, O. V. D. S. J., Perera, K. L. N. & Galhena, G. (2020) Genetic characterization of Aedes aegypti (Diptera: Culicidae) in Sri Lanka based on sequence polymorphism of COI gene. Journal of Vector Borne Diseases 57 (2):151–158. Available from: doi: 10.4103/0972-9062.310871 Powell, L. A., Miller, A., Fox, J. M., Kose, N., Klose, T., Kim, A. S., Bombardi, R., Tennekoon, R. N., de Silva, A. D., Carnahan, R. H., Diamond, M. S., Rossmann, M. G., Kuhn, R. J. & Crowe, J. E. Jr. (2020) Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host & Microbe. 28(5), 699-711.e7. Available from: doi: 10.1016/j.chom.2020.07.008 Mutucumarana, C. P., Bodinayake, C. K., Nagahawatte, A., Devasiri, V., Kurukulasooriya, R., Anuradha, T., De Silva, A. D., Janko, M. M., Østbye, T., Gubler, D. J., Woods, C. W., Reller, M. E., Tillekeratne, L. G. & Lantos, P. M. (2020) Geospatial analysis of dengue emergence in rural areas in the Southern Province of Sri Lanka. Trans R Soc Trop Med Hyg. 114(6), 408-414. Available from: doi: 10.1093/trstmh/trz123 Grifoni, A., Voic, H., Dhanda, S. K., Kidd, C. K., Brien, J. D., Buus, S., Stryhn, A., Durbin, A. P., Whitehead, S., Diehl, S. A., De Silva, A. D., Balmaseda, A., Harris, E., Weiskopf, D. & Sette, A. (2020) T Cell Responses Induced by Attenuated Flavivirus Vaccination Are Specific and Show Limited Cross-Reactivity with Other Flavivirus Species. Journal of Virology. 94(10) Available from: doi: 10.1128/JVI.00089-20 Mapalagamage, M., Handunnetti, S. M., Wickremasinghe, A. R., Premawansa, G., Thillainathan, S., Fernando, T., Kanapathippillai, K., De Silva, A. D. & Premawansa, S. (2020) High levels of Serum Angiopoietin 2/1 Ratio at the Critical Stage of Dengue Hemorrhagic Fever in Patients and Association with Clinical and Biochemical Parameters. J Clin Microbiol. 58(4). Available from: doi: 10.1128/JCM.00436-19 Nirmani M. D., Perera, K. L. N. & Galhena, G. H. (2019) Use of ovitrap surveillance to assess dengue outbreak risks in selected dengue endemic areas in Sri Lanka. Sri Lankan Journal of Biology 4(2): 32-46. Available from: doi: 10.4038/sljb.v4i2.39 Tian, Y., Seumois, G., De-Oliveira-Pinto, L. M., Mateus, J., Herrera-de la Mata, S., Kim, C., Hinz, D., Goonawardhana, N. D. S., de Silva, A. D., Premawansa, S., Premawansa, G., Wijewickrama, A., Balmaseda, A., Grifoni, A., Vijayanand, P., Harris, E., Peters, B., Sette, A. & Weiskopf, D. (2019) Molecular Signatures of Dengue Virus-Specific IL-10/IFN-g Co-producing CD4 T cells and their Association with Dengue Disease. Cell Rep. 29(13), 4482-4495.e4. Available from: doi: 10.1016/j.celrep.2019.11.098 Burel, J. G., Pomaznoy, M., Lindestam Arlehamn, C. S., Weiskopf, D., da Silva Antunes, R., Jung, Y., Babor, M., Schulten, V., Seumois, G., Greenbaum, J. A., Premawansa, S., Premawansa, G., Wijewickrama, A., Vidanagama, D., Gunasena, B., Tippalagama, R., de Silva, A. D., Gilman, R. H., Saito, M., Taplitz, R., Ley, K., Vijayanand, P., Sette, A. & Peters, B. (2019) Circulating T cell-monocyte complexes are markers of immune perturbations. Elife. Available from: doi: 10.7554/eLife.46045.001 Grifoni, A., Moore, E., Voic, H., Sidney, J., Phillips, E., Jadi, R., Mallal, S., De Silva, A. D., De Silva, A. M., Peters, B., Weiscopf, D. & Sette, A. (2019) Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses. Front Immunol. Available from: doi: 10.3389/fimmu2019.01568 Jayasinghearachchi, H. S., Corea, E. M., Krishnananthsivam, S., Sathkumara, H. D., Francis, V. R., Abeysekere, T. R. & De Silva, A. D. (2019) Whole-Genome Sequences of Eight Clinical Isolates of Burkholderia Pseudomallei from Melioidosis Patients in Eastern Sri Lanka. Microbial Resour Announc. 8(33). Available from: doi: 10.1128/MRA.00645-19 Kose, N., Fox, J. M., Sapparapu, G., Bombardi, R., Tennekoon, R. N., De Silva, A. D., Elbashir, S. M., Theisen, M. A., Humphris-Narayanan, E., Ciaramella, G., Himansu, S., Diamond, M. S. & Crowe Jr, J. E. (2019) A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection. Science Immunology. 4(35). Available from: doi: 10.1126/sciimmunol.aaw6647 Tian, Y., Babor, M., Lane, J., Seumois, G., Liang, S., Goonawardhana, N. D. S., De Silva, A. D., Phillips, E. J., Mallal, S. A., da Silva Antunes, R., Grifoni, A., Vijayanand, P., Weiskopf, D., Peters, B. & Sette, A. (2019) Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles. The journal of clinical investigation. 129(4), 1727-1741. Available from: doi: 10.1172/JCI123726 Vimonish, R., Galhena, G. H., Perera, K. L. N. & Magamage, M. P. S. (2018) PCR based approach for detection of bovine babesiosis in suspected carrier cattle and vector ticks in Sri Lanka. Journal of Agricultural Sciences – Sri Lanka, 13(1):55–65. Available from: doi: 10.4038/jas.v13i1.8300 Raut, R., Corbett, K. S., Tennekoon, R. N., Premawansa, S., Wijewickrama, A., Premawansa, G., Mieczkowski, P., Rückert, C., Ebel, G. D., De Silva, A. D. & de Silva, A. M. (2018) Dengue type 1 viruses circulating in humans are highly infectious and poorly neutralized by human antibodies. Proc Natl Acad Sci USA . 116(1), 227-232. Available from: doi: 10.1073/pnas.1812055115 Tillekeratne, L. G., Bodinayake, C. K., Simmons, R., Nagahawatte, A., Devasiri, V., Kodikara Arachchi, W., Nicholson, B. P., Park, L. P., Vanderburg, S., Kurukulasooriya, R., De Silva, A. D., Østybe, T., Reller, M. E. & Woods, C. W. (2018) Respiratory Viral Infection: An Underappreciated Cause of Acute Febrile Illness Admissions in Southern Sri Lanka. Am J Trop Med Hyg . 100 (3), 672-680. Available from: doi: 10.4269/ajtmh.18-0699 Grifoni, A., Costa-Ramos, P., Pham, J., Tian, Y., Rosales, S. L., Seumois, G., Sidney, J., De Silva, A. D., Premkumar, L., Collins, M. H., Stone, M., Norris, P. J., Romero, C. M. E., Durbin, A., Ricciardi, M. J., Ledgerwood, J. E., de Silva, A. M., Busch, M., Peters, B., Vijayanand, P., Harris, E., Falconar, A. K., Kallas, E., Weiskopf, D. & Sette, A. (2018) Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus-Specific CD8+ T Cells. J Immunol . 201 (12), 3487-3491. Available from: doi: 10.4049/jimmunol.1801090 Mapalagamage, M., Handunnetti, S., Premawansa, G., Thillainathan, S., Fernando, T., Kanapathippillai, K., Wickremasinghe, R., De Silva, A. D. & Premawansa, S. (2018) Is Total Serum Nitrite and Nitrate (NOx) Level in Dengue Patients a Potential Prognostic Marker of Dengue Hemorrhagic Fever. Dis Markers . Available from: doi: 10.1155/2018/5328681 Fernando, S. J. A., Faiz, N. M., Handunnetti, S. M., De Silva, A. D., Dasanayake, W. M. D. K., Wickramasinghe, G. D., Karunatilake, R. M. C. H. & de Silva, N. R. (2018) Preliminary study on chronic granulomatous disease in Sri Lanka. Allergy Asthma Clin Immunol. 14, 37. Available from: doi: 10.1186/s13223-018-0264-7 Corea, E. M., de Silva, A. D. & Thevanesam, V. (2018) Melioidosis in Sri Lanka. Trop Med Infect Dis. 3(1). Available from: doi: 10.3390/tropicalmed3010022 Bodinayake, C. K., Tillekeratne, L. G., Nagahawatte, A., Devasiri, V., Kodikara Arachchi, W., Strouse, J. J., Sessions, O. M., Kurukulasooriya, R., Uehara, A., Howe, S., Ong, X. M., Tan, S., Chow, A., Tummalapalli, P., De Silva, A. D., Østbye, T., Woods, C. W., Gubler, D. J. & Reller, M. E. (2018) Evaluation of the WHO 2009 classification for diagnosis of acute dengue in a large cohort of adults and children in Sri Lanka during a dengue-1 epidemic. PLoS Negl Trop Dis . 12(2). Available from: doi: 10.1371/journal.pntd.0006258 Montoya, M., Collins, M., Dejnirattisai, W., Katzelnick, L. C., Puerta-Guardo, H., Jadi, R., Schildhauer, S., Supasa, P., Vasanawathana, S., Malasit, P., Mongkolsapaya, J., de Silva, A. D., Tissera, H., Balmaseda, A., Screaton, G., de Silva, A. M. & Harris, E. (2018) Longitudinal Analysis of Antibody Cross-Neutralization Following Zika and Dengue Virus Infection in Asia and the Americas. J Infect Dis . Available from: doi: 10.1093/infdis/jiy164 Premkumar, L., Collins, M., Graham, S., Liou, G. A., Lopez, C. A., Jadi, R., Balmaseda, A., Brackbill, J. A., Dietze, R., Camacho, E., De Silva, A. D., Giuberti, C., Dos Reis, H. L., Singh, T., Heimsath, H., Weiskopf, D., Sette, A., Osorio, J. E., Permar, S. R., Miley, M. J., Lazear, H. M., Harris, E. & de Silva, A. M. (2018) Development of Envelope Protein Antigens To Serologically Differentiate Zika Virus Infection from Dengue Virus Infection. J Clin Microbiol . 56(3). Available from: doi: 10.1128/JCM.01504-17 Page 1 of 3 Journal Publications 1 2 3

Explore Dhammika Gunasekera’s journey from Royal College head prefect to Genetech’s owner and philanthropic force in Sri Lanka. Dhammika Gunasekera Owner of Genetech and Managing Trustee of Genetech Research Institute (GRI) Dhammika Gunasekera is the Owner of Genetech after the demise of his beloved wife Dr. Maya Gunasekera, the Founder of Genetech. He is also the owner of Dienge purveyors of handcrafted silver, fine art, gems and jewellery. Dhammika greatly values generosity and helps a large number of people and institutions financially. For example, he has given donations to the Sri Lanka Cancer Society, sponsored the Devapathiraja College (a school founded by his grandfather Sir Ernest De Silva) Rugby team in Rathgama, a rural area in Sri Lanka and met university tuition fees of students. He was a partner at Messrs. U. N. Gunasekera, a construction firm in Sri Lanka established by his father. The first two five-star hotels in Sri Lanka, namely, Lanka Oberoi (Cinnamon Grand) and Ceylon Inter-Continental (Kingsbury) were built by this company. He graduated from Imperial College London in 1989 with first class honours in civil engineering (BEng). Broadening his horizons to the field of accountancy, he became a passed finalist of the Institute of Chartered Accountants of Sri Lanka in 1986. Furthermore, he topped his batch in the Bachelor of Science degree that he completed at University of Colombo in 1984. He was also the head prefect of Royal College, Colombo in 1980.

Explore career opportunities at Genetech in molecular biology, biotechnology, and more. Join our team of scientists, accountants, receptionists, and other professionals. Job Vacancies Apologies - We are not recruiting for any position at this time. Please check again later. You can follow our Facebook page, Instagram page and LinkedIn page to stay updated on job opportunities, internship opportunities, and the services we offer at Genetech.

Explore innovative PhD projects funded by Genetech in Sri Lanka, covering forensic genetics, dengue vector studies, and rice blast resistance. Dive into cutting-edge research and groundbreaking discoveries! Research leading to the award of PhD X-Chromosome markers for forensic genetics in Sri Lanka: development, validation and application of a novel 16 X-STR multiplex assay for the Sri Lankans. K. L. Nandika Perera, Ph.D., Department of Basic Sciences, Faculty of Health Sciences, The Open University of Sri Lanka, 2021. Population genetic and epidemiological investigation of the dengue vectors Aedes aegypti (L.) and Aedes albopictus (Skuse) in Sri Lanka. M. D. Nirmani, Ph.D., Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Sri Lanka, 2021 (Thesis Submitted). DNA marker assisted breeding of rice blast resistant genes into local rice. Ama Jayawardana, Ph.D. Department of Plant Sciences, Faculty of Science, University of Colombo; Rice Research and development Institute, Batalagoda, 2019 (Conducted partially at Genetech). Genetic diversity and population structure of ex-situ conserved finger millet (Eleusine coracana (L.) Gaertn) accessions in Sri Lanka. Parami Wakista, Ph.D. Department of Botany, Faculty of Applied Science, University of Sri Jayewardenepura, 2017. Development of Mini STR primers in order to enhance sensitivity and amplification efficiency of Polymerase Chain Reaction (PCR) to aid analysis of degraded DNA evidence in Sri Lankan case work. N. D. Suraj Goonawardhana, Ph.D., Department of Zoology Environment Sciences, Faculty of Science, University of Colombo, Sri Lanka, 2016. Characterization and transfer of Drought Responsive Elements Binding (DREB) genes to develop transgenic drought resistant rice. W.S. Imesh De Silva, Ph.D., Department of Plant Sciences, Faculty of Science, Faculty of Science, University of Colombo, Sri Lanka, 2016. Understanding the role of host genetic factors and specific dengue virus epitomes during dengue infection. Anira Fernando, Ph.D., Department of Zoology Environment Sciences, Faculty of Science, University of Colombo, Sri Lanka, 2015. Sustainable insect resistance in local rice varieties. Manisha Gunasekera, PhD, Department of Plant Sciences, University of Colombo, Sri Lanka. 2010 (partially conducted at Genetech). Development of databases for autosomal Y-chromosomal and mitochondrial DNA markers and their application in forensic casework and population genetics in Sri Lankan populations. Ruwan J Illeperuma, PhD, Department of Zoology, University of Colombo, Sri Lanka, 2010. Detection, quantification and characterization of Hepatitis C virus strains in Sri Lanka. Dhammika B. Seneviratne, PhD, Postgraduate Institute of Science, University of Peradeniya, Sri Lanka, 2010. Severity of dengue disease and the role of different serotypes and genotypes of the causative viruses. Upul Nalaka De Silva Kanakaratne, PhD, Department of Microbiology, Faculty of Medicine, University of Peradeniya, Sri Lanka, 2009.

Early diagnosis is crucial for canine health. Our PCR-based tests detect Parvovirus, Ehrlichiosis, and more. Trust us for accurate results. Animal Testing What is Parvovirus and why is early diagnosis essential? Canine Parvovirus (CPV) is a highly contagious pathogen primarily affecting dogs. This virus can also infect other mammals including cats. If untreated, the risk of death may be high. Thus, a rapid and early diagnosis could save their lives. Detection of the virus can help you select an appropriate treatment regimen for your animals, prevent the spread of the virus and save them from secondary infections. Why we recommend a PCR test over an ELISA test The sensitivity of an ELISA test depends on the Ag/Ab concentration and the availability. Thus, it could lead to false positive or negative results. In contrast, our PCR (Polymerase Chain Reaction) test detects the viral genome and produces no false positive or negative results. This is because it is dependent on the availability of the virus but not its products or Abs. The positive result of an ELISA test can be caused by organisms other than the target. On the other hand, our PCR test detects genetic sequences unique to the target pathogen. Therefore, its specificity is much higher than an ELISA test. The accuracy of the ELISA test varies, and it depends on the Ag/Ab availability. Our PCR test offers a consistent accuracy of 99%. What is tick fever and why may early detection be crucial? Tick fever is a common canine disease in Sri Lanka which is caused through the bite of an infected tick carrying an insidious and deadly organism. Scientifically, it is known as Canine Ehrlichiosis and Canine Babesiosis. Early detection may prevent the dog from experiencing severe anemic conditions caused by the disease due to the highly pathogenic nature of it. Furthermore, the specific detection will help choose a suitable treatment regimen for your dog. Why microscopy and antibody tests are not ideal Some stages of the parasite life cycle cannot be observed through the microscope. Therefore, the probability of obtaining false results is high. It takes several days to develop antibodies against a certain infection in the body. Hence, it is difficult to diagnose the infection early. Antibodies may be present in the body even after the disease is cured. Thus, if the test is done after the infection is cured, the result may be false positive. What we offer We are the first firm to provide a PCR based animal disease testing service in Sri Lanka. We offer tests which detect Canine Parvovirus, Canine Distemper, Canine Babesiosis and Canine Ehrlichiosis. In addition to animal disease testing, we provide a cattle parentage testing service through the use of DNA typing. Contact us View price list