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Explore our comprehensive molecular biology internships, including disease diagnostics, DNA fingerprinting, and GM food testing. Hands-on training, expert supervision, and individual research assignments. Internship Programme in DNA Fingerprinting and Genetic Testing Who Can Register: Graduates, undergraduates, postgraduates, researchers, and A/L students This internship programme offers flexible durations of two weeks, four weeks, and six weeks. Internships are available year-round, subject to space availability, and can be customised to meet specific requirements. Programme Overview: The internship provides comprehensive training in DNA fingerprinting for forensic and kinship testing, genetic disease diagnostics, GMO testing as well as many other widely used molecular applications. Two-Week Programme – LKR 64,500.00 Laboratory exposure working alongside our scientists in areas such as molecular forensics, kinship testing, GMO testing, and genetic disease diagnostics. Hands-on experience in molecular techniques by carrying out selected test methods. Four-Week Programme – LKR 96,000.00 Includes all components of the two-week programme, with the added opportunity to conduct a short-term research project. This project focuses on applying DNA fingerprinting techniques, involving a literature review, independent lab work, and data analysis. Six-Week Programme – LKR 128,000.00 Extends the four-week programme, allowing for a more in-depth research experience, with additional time for experimental work, data interpretation, and presentation of findings. Eight-Week Programme – LKR 160,000.00 Extends the four-week programme, allowing for a more in-depth research experience, with additional time for experimental work, data interpretation, and presentation of findings. Upon successful completion of the programme, interns will receive a certification letter detailing their training and experience. View FAQs Contact us If you are interested in doing an internship at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form

Learn essential techniques in gene technology and DNA fingerprinting. Open to A Level students and current undergraduates in biology, biotechnology, and biomedical science. Advanced Certificate Course in Molecular Techniques for DNA Fingerprinting For Graduates, Undergraduates, Pre-University and A/L Students Why choose this course? This course provides in-depth coverage of fundamental molecular techniques in gene technology, with a special focus on DNA fingerprinting—the gold standard for individual identification. Students will gain expertise in a broad range of essential molecular biology techniques, preparing them for successful careers in state-of-the-art laboratories worldwide. A certificate will be issued upon completion of the course. Who can register for this course? This course is ideal for undergraduates and graduates in biology, biotechnology, or biomedical science who are seeking to advance their postgraduate studies or enhance their career prospects. It is also highly beneficial for current and recently completed A/L students (Edexcel, Cambridge, and Local A/L) who aim to pursue higher education in these fields. Course Content The course encompasses both theoretical and practical aspects of the following. Basic setup of a molecular biological lab Handling biological samples for DNA fingerprinting Chelex and solid-phase DNA extraction methods DNA quantification Multiplex PCR Commercial kits for DNA profiling Agarose gel electrophoresis Capillary electrophoresis Generating and analysing DNA profiles SNPs for human identification Mitochondrial DNA analysis and X and Y chromosome testing Animal and plant forensics Sex determination and detection of chromosomal anomalies DNA sequence analysis Individual hands-on training will be provided. Duration and fees This course will run from 9.00 am to 4.00 pm on 10 weekdays. The programme fee will be LKR 64,500 which is to be paid before the registration in order to confirm and reserve your place. Places will be offered on a first come first served basis. Email now If you are interested in participating in this training programme, send us an email with your details to info@genetechsrilanka.com View FAQs Contact us View Inquiry Form

Explore our comprehensive molecular biology internships, including disease diagnostics, DNA fingerprinting, and GM food testing. Hands-on training, expert supervision, and individual research assignments. Internship Programme on Molecular Disease Diagnostics Who Can Register: A/L, Pre-University and Undergraduate Students Our internship programme offers the flexibility to choose between two-week and six-week durations, tailored to your educational needs. Available throughout the year, this programme is designed to provide hands-on experience in molecular diagnostics, with the ability to customise based on specific requirements. Two-Week Programme: LKR 48,000 Key Focus Areas: Diagnostic Testing: Human infectious disease testing Cancer testing Canine disease testing Plant disease testing Methods covered: DNA extraction/handling of different samples RNA extraction PCR, RT-PCR, qPCR Gel electrophoresis PCR trouble shooting Introduction to the ISO 15189 system and planning a molecular diagnostic laboratory Six-Week Programme: LKR 96,000 Includes all components of the two-week programme. In addition, interns will undertake a four-week internship involving an individual research assignment. This project involves a literature survey, independent laboratory work, result analysis, and interpretation. Upon successful completion of the programme, interns will receive a certification letter detailing their training and experience. View FAQs Contact us If you are interested in doing an internship at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form

Master PCR Technology in this 18-hour course. Ideal for students and professionals, covering PCR principles, applications, and hands-on practicals like DNA extraction, PCR assays, and troubleshooting. Polymerase Chain Reaction (PCR) Technology (18 hours) This course is suitable for school-level, undergraduate and graduate students, and those engaged in scientific research, diagnostics and teaching which involves Polymerase Chain Reaction (PCR) Technology. Theory: Guidelines for PCR Principle of PCR Critical factors for successful PCR Designing PCR primers Standard practices in a PCR Laboratory Troubleshooting and prevention of carryover contamination Optimization strategies for PCR PCR product analysis: Detection of PCR products by gel electrophoresis Methods of purification and quantification of PCR products Methods of labelling of PCR products (PCR probes) and visualization of label Cloning of PCR products: TOPO cloning DNA sequence analysis of PCR product PCR Applications: Restriction Fragment Length Polymorphism (RFLP) and Randomly Amplified Polymorphic DNA (RAPD) analysis Short Tandem Repeat (STR) (micro-satellite) analysis Multiplex PCR Reverse Transcription (RT)-PCR PCR-ELISA (Enzyme Linked Immunosorbent Assay) In-situ PCR Quality Control/Quality Assurance of PCR assays Practicals: Extraction of DNA from cells, blood stains for PCR A standard PCR assay Analysis of PCR products by agarose and acrylamide gel electrophoresis Strategies for optimization of PCR Purification of PCR products Labelling of PCR products Primer design using online sequence databases PCR-RFLP assay Multiplex PCR assay RT-PCR assay PCR-ELISA assay PCR troubleshooting View FAQs Contact us If you are interested in doing this course at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form

Discover Genetech’s innovative DNA/RNA extraction and PCR amplification kits, tailored for research and industrial needs. Click to explore our customizable solutions! Product Development Our research projects often aim for a final product which can range from developing a new diagnostic test to a commercial nucleic acid extraction or amplification kit. Research and development projects have given rise to Genetech's new product line. DNA and RNA extraction kits We have developed a wide range of DNA/RNA extraction kits such as viral RNA/DNA extraction kits, Bacterial genomic and plasmid DNA extraction kits, plant DNA extraction kits, human and other animal genomic DNA extraction kits. The kits are starting from 25 prep size and are scaled up to 100s to meet the wide array of requirements found in the research community. For optimum results, we also provide customised extraction kits for low yielding starting materials like insect and bone samples. PCR amplification kits We offer customised conventional and real time PCR amplification kits (Ready mix PCR kits) for both DNA and RNA. This can be integrated with primer designing and PCR optimisation as required for the best results. Industrially important kits We offer to develop industrially important test kits to meet specific needs. For example, White Spot Syndrome Virus Detection Kit for shrimps was developed for the shrimp farm industry, based on customer requirements. You can contact us to discuss your specific requirement. We are able to design and develop customised kits for a wide variety of industrial needs. Contact us

Discover Genetech’s DNA testing accuracy for identity, parentage, and forensics, ensuring over 99.99% paternity certainty and match probabilities beyond standards. Accuracy of evidence DNA testing is the most accurate and reliable means of identity verification and parentage testing. The degree of accuracy of the test will depend on the genetic diversity of the Sri Lankan population as well as the number of genetic locations (STR loci) which are tested. There is no mandatory number of STR loci required for a test, but the testing of nine STR loci or more is generally considered to be sufficiently accurate. We test up to 15 STR loci. Accuracy in a test of familial relationships: A paternity or maternity test can prove with 100% certainty that an individual is not the biological parent of a child. However, no DNA test available can prove with 100% certainty that a man or woman is the biological parent of a child. Generally, a degree of certainty of over 99% is required to accept the paternity or maternity of an individual. DNA testing by Genetech typically proves paternity with at least 99.99% certainty. This is well in excess of the required accuracy. Accuracy in criminal casework: In criminal casework, the demand for accuracy is greater, and the forensic scientist has to prove beyond a doubt that a suspect's DNA profile matches with that of the criminal. This involves expressing the probability of finding a random person in the population who might have this same profile. This probability is known as the Match Probability. This probability must be very low. When the Match Probability is lower, the accuracy of the conclusions of the DNA test is greater. There is no internationally agreed lower limit for this probability, but the result is generally accepted if it is lower than 1 in 1 billion. At Genetech, a sufficient number of loci can be tested to ensure that the Match Probability is lower than 1 in 10 billion.

Explore Genetech’s core values: a beacon of positivity, excellence, and integrity, driving innovation and collaboration in the biotech landscape. Our Values Positivity Our commitment to sustain a positive environment for our employees as well as our clients is one of the key factors that set us apart from our competitors. We believe it is essential to encourage people to let go of their past unfavourable experiences and eliminate any pessimistic thoughts about their future. This provides them the opportunity to enjoy the present moment without any distractions, irrespective of the circumstances. Furthermore, it bolsters employee confidence and morale, allowing a highly efficient working culture to be established. The key steps to being always happy involve forgiving others and yourself for any mistakes they or you have made and appreciating the uncertainty of the future as well as the imperfections around us. Thus, we strive to meet our short-term and long-term objectives by planning optimistically and effectively whilst expecting nothing in return. We believe expectations may potentially act as barriers to understanding reality and enjoying every moment, due to the unpredictable future we all have. For example, if an employee is working towards a strict deadline of a major project, they may suffer from anxiety if they start predicting the consequences of not completing their deliverables within the allocated time period. This would potentially be a hindrance to enjoying the work they carry out. Nevertheless, we always aim to exceed our clients’ expectations by offering exceptional customer service. The positive attitude our employees possess to undertake any task with great enthusiasm is what makes us very special. Collaboration Collaboration is at the core of everything we do. We enjoy interacting with various types of people whilst appreciating the cultural diversity that they bring to the community. Our employees are mentored by senior members of the company as well as junior members to guide them to achieve their career goals and provide technical knowledge where necessary. Our team is also trained to have the ability to work independently where required. We understand that every decision we make in life has pros and cons but a person with a positive attitude will be happy with whichever decision they make, provided there are no negative intentions behind the decision. We believe it is possible for any organisation to create a home away from home, if you learn to be compassionate towards others and enjoy every moment irrespective of the im perfections everyone brings to society. Excellence Delivering excellence has always been our main focus as we love inspiring and elevating the communities we touch. This includes integrating cutting-edge DNA fingerprinting technology, engaging in research and contributing to innovative, future-ready solutions, and adopting eco-friendly approaches. We transcend the industry by reimagining the possibilities of expanding our expertise, and our staff are always excited and motivated to devise solutions to complex challenges we could face. To achieve the best possible outcomes, we embrace change and enhancement where necessary, and our employees are passionate to constantly find techniques to develop the services we offer. We continually aim to enhance our work environment with the intention of ensuring our stakeholders enjoy everything we do and love everyone they meet. This stems from the priority given to mental and physical health at Genetech. Indeed, it has also made it very easy for us to grow professionally and build an excellent organisation. Integrity We always act with integrity, and we have strong moral and ethical principles to be followed at all times regardless of the consequences. We believe trust and honesty are central to integrity as well as consistency. Integrity is one of the most important assets we seek when we recruit new employees to join our team. Moreover, we make our decisions on candidates who apply for a job at Genetech based purely on their skills, passion and potential to invigorate us to move forward and achieve greater success as a biotechnology company. We also have built our customers’ trust by obtaining ISO 15189 accreditation and maintaining the standards in all aspects. We believe a workplace with employees whose actions are open and transparent is one that fosters beneficial leadership qualities in others. Treating everyone with respect is absolutely vital to us as our objective is to maintain an organisation that supports you unconditionally, regardless of differences such as sex, age, race, religion and ethnic origin.

Explore diverse research on genetic variation, virological surveillance, and forensic DNA evidence in Sri Lanka, presented at various academic conferences and symposiums. Conference Papers and Communications Page 2 of 2 De Silva, A. D., Perera, N., Abeysekera, D. M. & Elvitigala, J. P. (2009) Molecular characterization of Mycobacterium tuberculosis(MTB) isolates in Sri Lanka utilizing the Mycobaterium interspersed repetitive units(MIRU) typing method. Respire, Inaugural symposium of the association of pulmonologists. De Silva, A. D., Samarasinghe, K. S. R. G. S. L., Abeysekera, D. M. & Elvitigala, J. P. (2009) Screening for IS6110 zero copy number strains of Mycobacterium tuberculosis in Sri Lanka Genetech Research Institute, Colombo 8, Chest Hospital, Welisara. The Bulletin of the Sri Lanka College of Microbiologists, volume 7, Issue 1. Muthunayake, T., Dangalle, C., Fernandopulle, N. & Weerakoon, D. (2009) Genetic analysis of morphologically non-identifiable translocated Puntius bandula population at Salgala using CO1 region of mt DNA. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 66. Available from: https://www.researchgate.net/publication/335926117_Genetic_analysis_of_morphologically_non-identifiable_translocated_Puntius_bandula_population_at_Salgala_using_CO1_region_of_mtDNA Wickramasinghe, E. D. T. S. L., Fernandopulle, N. D. & Hettiarachchi, P. L. L. (2009) DNA barcoding of Sri Lankan Tea - A method to secure ownership in the international trade. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 68. Samaradivakara, S., Gunasekera, I., Mendis, B., Karunaratne, U., Jayathunga, T., Sledgers, R. & Fernandopulle, N. (2009) Preliminary study on DNA barcoding of cinnamon varieties in Sri Lanka. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 69-70. Fernando, A., Samaradivakara, S., De Silva, A. D., Baranage, G., Herath, I., Fernandopulle, N. D., Padmalal, K. & Ranawaka, G. R. R. (2009) DNA Barcoding of the Sri Lankan Slender Loris (Loris tardigradus or Loris lydekkerianus?) A preliminary report. Proceedings of the Fourteenth International Forestry and Environment Symposium, University of Sri Jayawardenepura, Sri Lanka. 1 (1), 74. Available from: http://repository.ou.ac.lk/handle/94ousl/1845 Rajasinghe, M. H. L. D., Fernandopulle, N. & Perera, A. L. T. (2009) Detection of Genetically Modified Soy Food in Sri Lankan Supermarket, Paper Presented at the Proceedings of the Peradeniya, University Research Sessions, University of Peradeniya, Peradeniya, Sri Lanka.Vol:14 (1) pp: 16-18. Perera, A. N. K., Logendra, B., Fernandopulle, N. D. & Attanayaka, D. P. S. T. G. (2009) Development of a PCR-based molecular Detection Assay for Thielaviopsis paradoxa in Coconut Fibre Dust. Proceedings of 9th Agricultural Research Symposium, Wayamba University of Sri Lanka. 326-331. Tissera, H. A., De Silva, A. D., Abeysinghe, M. R. N., de Silva, A. M., Palihawadana, P., Gunasena, S., Tam, C. C., Gamage, T. M., De Silva, T., Rajapaksa, L. C., Amarasinghe, A., Letson, G. W. & Margolis, H. S. (2009) Dengue Surveillance in Colombo, Sri Lanka: Baseline seroprevalence among children. Procedia in Vaccinology . 2(1) 110–114. Available from: doi: 10.1016/j.provac.2010.03.020 Gunathilaka, P. V. V. W., Fernandopulle, N. D. & Attanayaka, D. P. S. T. G. (2007) Development of an in-house method for purification and characterization of Taq DNA polymerase. Proceedings of 7th Agricultural Research Symposium, Wayamba University of Sri Lanka. 1 (1), 27-31. Fernandopulle, N. D. (2007) DNA typing for forensic and civil casework in Sri Lanka; a critical review. Proceedings of the 9th Indo-Pacific Congress on Legal Medicine & Forensic Sciences. Illeperuma, R. J. (2007) Y-Chromosome and Mitochondrial DNA reference data bases for Sri Lankan Human Population, 9th Indo-Pacific Congress on Legal Medicine & Forensic Sciences. OP-72 p83. Markalanda, D. A., Illeperuma, R. J. & Fernandopulle, N. D. (2007) Establishment of a Differential extraction of Male and Female DNA from sexual assault samples - 9th Indo-Pacific Congress on Legal Medicine & Forensic Sciences. Fernandopulle, D. N., Senevirathna, D. B., Ranaweera, D. M., Abeysekara, D., Perera, N., Kanakaratne, N., Jayasinghe, S., Samaraweera, P. & De Silva, A. (2007) Detection of HCV Genotypes among Sri Lankan Patients by Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR). The Bulletin of the Sri Lanka College of Microbiologists Vol 5. Seneviratne, D. & Gunasekera, M. B. (2006) Development of a low-cost in-house RT-PCR assay for the detection of hepatitis C virus. Annual Sessions of the Post Graduate Institute of Science, University of Peradeniya, Sri Lanka. Abbas, R., Senevirathne, D., Ranaweera, D. & Fernandopulle, N. D. (2006) DNA-based detection of Herpes Simplex virus 1 and 2 in clinical samples and its usefulness as a screening test for viral encephalitis. Proceedings of the 62nd Annual Sessions of the Sri Lanka Association for the Advancement of Science. Wahala, M., Messer, W., Kanakaratne, N., Perera, N., Seneviratne, D., Ranawake, G. R., Shahani, A., Ruberu, D., Gunasekera, M. B. & De Silva, A. M. (2005) Virological parameters of recent dengue hemorrhagic fever outbreak in Sri Lanka. Annual sessions of PUBMED, National institutes of Health, USA. Seneviratne, D., Gamage, P., Baranage, G., Jayasinghe, S., Shahani, A., Somaiah, S., Fernandopulle, N. D. & Gunasekera, M. B. (2004). Screening for Hepatitis C virus (HCV) infection by an in-house reverse transcription polymerase chain reaction (RT-PCR) based assay (2004) The Bulletin of the Sri Lanka College of Microbiologists Vol 2 (1). Fernandopulle, N. D., De Silva, V., Perera, N., Jayathilake, M. M., Pieris, D., Balawardana, J., Perera, M. & Gunasekera, M. B. (2004) Screening for Philadelphia Chromosome by an in-house Reverse Transcription-Polymerase Chain Reaction (RT-PCR) based assay. Proceedings of the 60th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Illeperuma, R. J., Fernandopulle, N. D., Senevirathna, D., Baranage, G., Perera, N. & Gunasekera, M. B. (2004). A comparison of theoretical and observed statistical data in paternity testing by DNA analysis. Proceedings of the 60th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Jayathilaka, S., Weerasinghe, R. & Fernandopulle, N. (2004) Predicting ethnic origin from DNA by neural networks. Proceedings of the 6th International Information Technology Conference IITC 2004, Colombo, Sri Lanka. Baranage, G., Seneviratne, D., Gamage, P., Ranawaka, G., Perera, N., Illeperuma, R., Ruberu, D., Shahani, A. & Gunasekera, M. B. (2004) Screening of febrile cases for early diagnosis of dengue and identification of dengue virus type using in-house diagnostic kits based on polymerase chain reaction. The Bulletin of the Sri Lanka College of Microbiologists Vol 2 (1). Illeperuma, R. J., Fernandopulle, N. D., Senevirathna, D., Baranage, G., Perera, N. & Gunasekera, M. B. (2004) DNA-based testing as a social phenomenon in Sri Lanka. Proceedings of the 60th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Ranawaka, G. R., Gamage, P., De Silva, V., Fernando, A., Seneviratne, D. & Gunasekera, M. B. (2003) Evaluation of a polymerase chain reaction (PCR)-agarose gel electrophoresis assay with a PCR-hybridization assay for the detection of Mycobacterium tuberculosis. Proceedings of the 59th Annual Sessions of the Sri Lanka Association for the Advancement of Science. Gamage, P., Seneviratne, D., Herath, C. A., Fernandopulle, N. D. & Gunasekera, M. B. (2003) Polymerase chain reaction based detection of cytomegalovirus infection in Sri Lanka. Proceedings of the 59th Annual Sessions of the Sri Lanka Association for the Advancement of Science. 1 2

Discover Genetech’s journal publications on genetic research and advancements in Sri Lanka, shaping the future of molecular diagnostics and biodiversity. Perera, N., Galhena, G. & Ranawaka, G. (2021) X-chromosomal STR based genetic polymorphisms and demographic history of Sri Lankan ethnicities and their relationship with global populations. Scientific Reports 11:12748. Available from: doi: 10.1038/s41598-021-92314-9 Perera, N., Galhena, G. & Ranawaka, G. (2021) Development of a 16 X-STR multiplex PCR system for kinship analysis and its applicability for the Sinhalese population in Sri Lanka. International Journal of Legal Medicine. 135:161–166. Available from: doi: 10.1007/s00414-020-02450-6 Nirmani, M. D., Perera, N. S. & Galhena, G. H. (2021) Population genetic dynamics of dengue vectors Aedes aegypti and Aedes albopictus in Sri Lanka: Baseline study for designing Wolbachia control method. International Journal of Tropical Insect Science. 41:1809–1821. Available from: doi: 10.1007/s42690-020-00395-2 Jayasinghearachchi, H. S., Francis, V. R., Sathkumara, H. D., Krishnananthasivam, S., Masakorala, J., Muthugama, T., De Silva, A. D. & Corea, E. M. (2021) Nonclonal Burkholderia pseudomallei Population in Melioidosis Case Cluster, Sri Lanka. Emerging Infectious Diseases. 27 (11). Available from: doi: 10.3201/eid2711.210219 Nirmani, M. D., Perera, N. S. & Galhena, G. H. (2020) The scope of Rp EPIC markers in population genetic studies: a preliminary study with dengue vectors. Journal of the National Science Foundation of Sri Lanka, 48(3): 275-288. Available from: doi: 10.4038/jnsfsr.v48i3.9311 Dharmarathne, H. A. K. M., Weerasena, O. V. D. S. J., Perera, K. L. N. & Galhena, G. (2020) Genetic characterization of Aedes aegypti (Diptera: Culicidae) in Sri Lanka based on sequence polymorphism of COI gene. Journal of Vector Borne Diseases 57 (2):151–158. Available from: doi: 10.4103/0972-9062.310871 Powell, L. A., Miller, A., Fox, J. M., Kose, N., Klose, T., Kim, A. S., Bombardi, R., Tennekoon, R. N., de Silva, A. D., Carnahan, R. H., Diamond, M. S., Rossmann, M. G., Kuhn, R. J. & Crowe, J. E. Jr. (2020) Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host & Microbe. 28(5), 699-711.e7. Available from: doi: 10.1016/j.chom.2020.07.008 Mutucumarana, C. P., Bodinayake, C. K., Nagahawatte, A., Devasiri, V., Kurukulasooriya, R., Anuradha, T., De Silva, A. D., Janko, M. M., Østbye, T., Gubler, D. J., Woods, C. W., Reller, M. E., Tillekeratne, L. G. & Lantos, P. M. (2020) Geospatial analysis of dengue emergence in rural areas in the Southern Province of Sri Lanka. Trans R Soc Trop Med Hyg. 114(6), 408-414. Available from: doi: 10.1093/trstmh/trz123 Grifoni, A., Voic, H., Dhanda, S. K., Kidd, C. K., Brien, J. D., Buus, S., Stryhn, A., Durbin, A. P., Whitehead, S., Diehl, S. A., De Silva, A. D., Balmaseda, A., Harris, E., Weiskopf, D. & Sette, A. (2020) T Cell Responses Induced by Attenuated Flavivirus Vaccination Are Specific and Show Limited Cross-Reactivity with Other Flavivirus Species. Journal of Virology. 94(10) Available from: doi: 10.1128/JVI.00089-20 Mapalagamage, M., Handunnetti, S. M., Wickremasinghe, A. R., Premawansa, G., Thillainathan, S., Fernando, T., Kanapathippillai, K., De Silva, A. D. & Premawansa, S. (2020) High levels of Serum Angiopoietin 2/1 Ratio at the Critical Stage of Dengue Hemorrhagic Fever in Patients and Association with Clinical and Biochemical Parameters. J Clin Microbiol. 58(4). Available from: doi: 10.1128/JCM.00436-19 Nirmani M. D., Perera, K. L. N. & Galhena, G. H. (2019) Use of ovitrap surveillance to assess dengue outbreak risks in selected dengue endemic areas in Sri Lanka. Sri Lankan Journal of Biology 4(2): 32-46. Available from: doi: 10.4038/sljb.v4i2.39 Tian, Y., Seumois, G., De-Oliveira-Pinto, L. M., Mateus, J., Herrera-de la Mata, S., Kim, C., Hinz, D., Goonawardhana, N. D. S., de Silva, A. D., Premawansa, S., Premawansa, G., Wijewickrama, A., Balmaseda, A., Grifoni, A., Vijayanand, P., Harris, E., Peters, B., Sette, A. & Weiskopf, D. (2019) Molecular Signatures of Dengue Virus-Specific IL-10/IFN-g Co-producing CD4 T cells and their Association with Dengue Disease. Cell Rep. 29(13), 4482-4495.e4. Available from: doi: 10.1016/j.celrep.2019.11.098 Burel, J. G., Pomaznoy, M., Lindestam Arlehamn, C. S., Weiskopf, D., da Silva Antunes, R., Jung, Y., Babor, M., Schulten, V., Seumois, G., Greenbaum, J. A., Premawansa, S., Premawansa, G., Wijewickrama, A., Vidanagama, D., Gunasena, B., Tippalagama, R., de Silva, A. D., Gilman, R. H., Saito, M., Taplitz, R., Ley, K., Vijayanand, P., Sette, A. & Peters, B. (2019) Circulating T cell-monocyte complexes are markers of immune perturbations. Elife. Available from: doi: 10.7554/eLife.46045.001 Grifoni, A., Moore, E., Voic, H., Sidney, J., Phillips, E., Jadi, R., Mallal, S., De Silva, A. D., De Silva, A. M., Peters, B., Weiscopf, D. & Sette, A. (2019) Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses. Front Immunol. Available from: doi: 10.3389/fimmu2019.01568 Jayasinghearachchi, H. S., Corea, E. M., Krishnananthsivam, S., Sathkumara, H. D., Francis, V. R., Abeysekere, T. R. & De Silva, A. D. (2019) Whole-Genome Sequences of Eight Clinical Isolates of Burkholderia Pseudomallei from Melioidosis Patients in Eastern Sri Lanka. Microbial Resour Announc. 8(33). Available from: doi: 10.1128/MRA.00645-19 Kose, N., Fox, J. M., Sapparapu, G., Bombardi, R., Tennekoon, R. N., De Silva, A. D., Elbashir, S. M., Theisen, M. A., Humphris-Narayanan, E., Ciaramella, G., Himansu, S., Diamond, M. S. & Crowe Jr, J. E. (2019) A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection. Science Immunology. 4(35). Available from: doi: 10.1126/sciimmunol.aaw6647 Tian, Y., Babor, M., Lane, J., Seumois, G., Liang, S., Goonawardhana, N. D. S., De Silva, A. D., Phillips, E. J., Mallal, S. A., da Silva Antunes, R., Grifoni, A., Vijayanand, P., Weiskopf, D., Peters, B. & Sette, A. (2019) Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles. The journal of clinical investigation. 129(4), 1727-1741. Available from: doi: 10.1172/JCI123726 Vimonish, R., Galhena, G. H., Perera, K. L. N. & Magamage, M. P. S. (2018) PCR based approach for detection of bovine babesiosis in suspected carrier cattle and vector ticks in Sri Lanka. Journal of Agricultural Sciences – Sri Lanka, 13(1):55–65. Available from: doi: 10.4038/jas.v13i1.8300 Raut, R., Corbett, K. S., Tennekoon, R. N., Premawansa, S., Wijewickrama, A., Premawansa, G., Mieczkowski, P., Rückert, C., Ebel, G. D., De Silva, A. D. & de Silva, A. M. (2018) Dengue type 1 viruses circulating in humans are highly infectious and poorly neutralized by human antibodies. Proc Natl Acad Sci USA . 116(1), 227-232. Available from: doi: 10.1073/pnas.1812055115 Tillekeratne, L. G., Bodinayake, C. K., Simmons, R., Nagahawatte, A., Devasiri, V., Kodikara Arachchi, W., Nicholson, B. P., Park, L. P., Vanderburg, S., Kurukulasooriya, R., De Silva, A. D., Østybe, T., Reller, M. E. & Woods, C. W. (2018) Respiratory Viral Infection: An Underappreciated Cause of Acute Febrile Illness Admissions in Southern Sri Lanka. Am J Trop Med Hyg . 100 (3), 672-680. Available from: doi: 10.4269/ajtmh.18-0699 Grifoni, A., Costa-Ramos, P., Pham, J., Tian, Y., Rosales, S. L., Seumois, G., Sidney, J., De Silva, A. D., Premkumar, L., Collins, M. H., Stone, M., Norris, P. J., Romero, C. M. E., Durbin, A., Ricciardi, M. J., Ledgerwood, J. 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Learn about Psittacine Beak and Feather Disease (PBFD) and how Genetech offers a PCR-based test for early detection. Submit feather or blood samples for reliable PBFD screening. Psittacine Beak and Feather Disease (PBFD) What is PBFD? Psittacine Beak and Feather Disease (PBFD) is a viral infection caused by a circovirus, primarily affecting parrots, cockatoos, and other psittacine birds. This virus leads to feather abnormalities and changes in beak formation. PBFD spreads through feather dust, faeces, and contaminated surfaces. The infection can be deadly in young birds and, in some cases, adult birds, as they may carry the virus without showing symptoms. As there is no specific treatment for PBFD, early detection is crucial for effective management through stringent quarantine and hygiene practices. Sample Collection Process To submit a sample for PBFD screening, follow these steps: Pluck 5-6 feathers from the bird’s chest area. Place the feathers in an envelope or a plastic zip-lock bag. Label the envelope or zip-lock bag with your bird ID (name, ring number, cage number, or other preferred identification). Complete the sample acceptance form and submit it along with the samples (available at the Genetech Reception or downloadable here ). You can submit the samples in person or by courier to: Genetech 54 Kitulwatte Road, Colombo 00800 For mail or courier submissions, place the sealed samples and completed sample acceptance form inside an envelope. We will notify you once the samples have been received. What we offer At Genetech, we offer a PCR-based screening test for PBFD using feather or blood samples. Contact us View Price List Sample Acceptance Sheet

Explore a diverse range of services at Genetech, including paternity testing, molecular diagnostics, biology courses, food testing, DNA sequencing, and more. Our Services Molecular Diagnostics Sex Determination of Birds DNA Sequencing Product Development DNA Typing Animal Testing Oligonucleotide and Gene synthesis Student Projects GM and Other Food Testing Courses & Internships Customised Biotechnology Solutions Collaborative Research View Price List

Join our 60-hour Intensive Practical Course in Molecular Biological Techniques at Genetech. Gain hands-on experience in cloning, DNA/RNA extraction, PCR, and gel electrophoresis. Ideal for researchers, students, and professionals in biological, medical, and forensic sciences. Intensive Practical Course in Molecular Biological Techniques (60 hours) This intensive training course provides a thorough hands on experience in key molecular biological techniques used in various fields of biological, medical and forensic sciences. The course is primarily aimed at individuals who are new to the area, theoretically familiar but lacking in practical bench training or wishing to enhance their practical skills further. At the end of the course, the participants will be able to acquire an adequate level of proficiency to allow for the troubleshooting and optimisation of routine laboratory protocols to promote timeliness and cost effectiveness. All practical work is conducted individually with the guidance of experienced persons in the relevant field. When? This course will run from 9.00am to 4.00pm for 10 consecutive weekdays as a full-time programme. Course dates: TBD For whom? Senior and junior researchers who wish to establish in the field of molecular biology Post A/L students interested in pursuing future studies in biological/biomedical sciences and/or forensic sciences Individuals who seek career opportunities in medical diagnostic laboratories and forensic DNA laboratories Those who wish to complement their knowledge in modern molecular biological techniques (e.g., medical doctors, medical laboratory technicians, forensic analysts, industry persons) Techniques Covered Cloning techniques: Isolation of plasmid DNA, Restriction enzyme digestion and transformations DNA extraction techniques: Isolation of human genomic DNA from blood and forensic samples, Bacterial/Viral DNA and Plant DNA RNA work: Isolation/purification and reverse transcriptase PCR assays Polymerase Chain Reaction: Technical elements and critical factors for successful PCR-based procedures, Multiplex PCR, Real Time PCR and PCR with RFLP Gel Electrophoresis: Agarose and polyacrylamide gel electrophoresis, automated capillary electrophoresis Course Fee Rs. 75,000 per person View FAQs Contact us If you are interested in doing this course at Genetech, please email us at info@genetechsrilanka.com to receive further details.