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- Samudi Mohotti | Genetech
Samudi Mohotti Senior Scientist Samudi Mohotti commenced her professional career at Genetech as a Scientific Officer at the division of parentage testing in 2004. In subsequent years, she was promoted to the post of Senior Scientist and currently oversees the entire process of parentage testing. She is one of the most experienced scientists in the field of DNA typing and has contributed to submit over 3,000 DNA test reports for civil and criminal cases to the Sri Lankan Judiciary. She took part in the development of an allele frequency databases of autosomal STR markers for Sri Lankans ethnicities and co-authored a journal paper in a high-impact journal, Forensic Science International: Genetics. In addition to DNA typing, she is involved in many research projects conducted by Genetech on contract basis to meet the requests from both state and private institutes. She is also a key member of the team which maintains the ISO 15189 quality management system of our laboratory. Samudi obtained her BSc degree in Biological Sciences from the University of Colombo, Sri Lanka and her Master’s degree in Applied Microbiology from the University of Kelaniya, Sri Lanka.
- Molecular Diagnostics | Genetech
Molecular Diagnostics Did you know? We pioneered the use of molecular diagnostics in Sri Lanka. This field, which was almost unknown to the medical fraternity in Sri Lanka is now widely used in delivering high quality patient management. Molecular diagnostics is now an accepted and even essential part of the health care system since it was introduced to Sri Lanka by us in 2002. How we strengthened our clients' trust In order to standardise our tests and strengthen our clients' trust, We have applied for and obtained ISO 15189 accreditation. Thus, our tests including those related to molecular disease diagnostics are excellent in all aspects. The importance of nucleic acids Infectious diseases are caused by a wide variety of organisms, ranging from multi-cellular parasites and fungi to uni-cellular bacteria to non-cellular viruses. These organisms cover a wide range of phyla, and have extremely diverse ways of infecting human beings. In spite of these differences, they all possess nucleic acids (DNA or RNA molecules), their hereditary material. This DNA or RNA forms the basis of their individuality, and because it is the basis of diversity, it is possible to identify these organisms from their DNA or RNA. What we offer with PCR technology Unlike other diagnostic methods, which rely on microscopy, culture, biochemical characteristics and indirect antibody detection, molecular diagnostics seeks evidence of a disease at the very basic causative level by detecting the nucleic acids based on PCR (Polymerase Chain Reaction) technology. This technology is also used to detect changes or mutations in our DNA, which can cause disease conditions known as genetic disorders. While some of these genetic disorders are passed from generation to generation, some happen spontaneously. Genetech offers DNA-based testing services for a wide variety of such genetic disorders and cancer markers. Contact us View Price List and Sample Collection Guide
- DNA Sequencing | Genetech
DNA Sequencing Genetech is an authorised agent for a world-leading company of genomic analysis which provides a wide variety of services including DNA sequencing and oligo nucleotide synthesis. This has enabled Genetech to provide the following services to Sri Lanka at an affordable price range. DNA Sequencing services Capillary Electrophoresis Sequencing CES analyses DNA sequences using Big Dye chemistry (Sanger Sequencing) and the ABI 3730xl analyser. CES can be performed either in individual PCR tubes or in 96 well plates for high throughput sequencing. The reaction can be conducted using both universal as well as custom made primers. The method is commonly used to sequence relatively shorter fragments of DNA for a variety of purposes. Sequencing of PCR products and plasmid CES is generally used for sequencing of PCR products and plasmid DNA up to 1,000 bp in length. A special CES service is also available for the ‘difficult sequencing’ such as high GC rich DNA, homopolymers, repetitive sequences and those with strong secondary structures. In addition, we accept the unamplified DNA and unprocessed biological samples for sequencing services. We also undertake to sequence PCR products containing nonspecific bands. Upon request, post sequence analysis (sequence alignments, phylogenetic tree construction, genome annotation etc.) services are also available to help the researchers interpret the results. Sequencing bacterial and fungal colonies 16S r-RNA gene sequencing is a common method used to identify bacterial species. As per the customer requirement, we undertake to sequence different length options up to 1400 bp. For the sequencing of fungal colonies, we provide three options: 18S rRNA gene (> 1,600 bp guaranteed), 26S rRNA gene (> 1,300 bp guaranteed) and ITS region (> 500 bp guaranteed). We also offer post-sequencing analysis services to assist species identification. Next-Generation Sequencing NGS, massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has been developed for genomic research during recent years. The technology performs parallel sequencing of millions of DNA fragments which are assembled into single genome using bioinformatics analysis. In contrast to the first-generation Sanger sequencing technology, NGS provides a much more efficient tool enabling the sequencing of the entire human genome within a single day. We offer numerous NGS sequencing techniques such as Whole Genome Sequencing, Metagenome Sequencing, Exome Sequencing, Transcriptome Sequencing and Epigenome Sequencing. Different NGS platforms are available to meet the varying requirement of these techniques. Our scientists will help you choose the best NGS option and platforms depending on your requirement. We also offer to assist in the bioinformatics analysis of NGS data. Contact us
- GRI | Genetech
Genetech Research Institute Genetech Research Institute (GRI) is a private, not-for-profit organisation that has been established with the vision of allowing objective oriented, independent scientific research in the field of life sciences in Sri Lanka. GRI has a staff of scientists and technical staff as well as a state-of-the-art Molecular Biology and Biochemistry research laboratory. GRI welcomes external researchers to inquire about collaborating with its scientific staff to carry out research in an efficient, dynamic environment. GRI is supported technically and scientifically by Genetech, which is Sri Lanka's first biotechnology company, and the premier practitioner of biotechnology in Sri Lanka. Publications Our scientists have contributed immensely in numerous journal publications and scientific conferences related to Molecular Biology. Student projects We have funded and facilitated undergraduate and postgraduate projects for students from many universities in Sri Lanka. Collaborative projects Collaboration is at the core of everything we do, and this includes working effectively with external researchers. Technical Services Our technical staff analyse samples provided by external researchers and deliver accurate results. Research Policies Our policies allow external researchers to access various facilities that will help meet their objectives. Legal & Ethical Guidelines We conform with all existing Laws of Sri Lanka regarding the performance of scientific research.
- Research Policies | Genetech
GRI Research Policies for External Researchers Genetech offers scientific expertise, technical services and laboratory facilities for research projects. External researchers will have access to all the following services: Bench space and access to all equipment at GRI Scientific and technical expertise of GRI permanent staff Common chemicals and supplies Assistance in ordering and receiving research supplies Library, computer and internet facilities at GRI Short term sample storage at 4 C, -20 C and -80 C. Coordination of international shipment of specimen (subject to local and international export/import regulations) Above services can be obtained under following broad categories, with the flexibility to accommodate the individual researcher's requirements.
- Certificate Course in Gene Technology | Genetech
Certificate Course in Gene Technology (60 hours) Theory: DNA, RNA structure and function Messenger RNA, Transfer RNA & proteins Chromosomes, genes, alleles, karyotypes, phenotype & genotype Extracting DNA from different sources Basic methods in bacteriology DNA modifying enzymes Genetic engineering & gene splicing Electrophoresis & quantification of DNA Polymerase chain reaction DNA fingerprinting in forensic casework Biotechnology in medicine & industry Practicals (hands-on practical experience on an individual basis for each student): Laboratory rules & safety precautions Use of micropipettes Preparation of reagents Plating & quantifying of bacteria Forensic DNA testing: Extraction of DNA, PCR & gel electrophoresis Isolation of plasmid DNA Spectrophotometric determination of DNA DNA sequence data analysis Course Fee: Practicals: Rs. 57 ,500 Lectures: Rs. 34,500 View FAQs Contact us If you are interested in doing this course at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form
- Internship in DNA Fingerprinting and Genetic Testing | Genetech
Internship Programme in DNA Fingerprinting and Genetic Testing Who Can Register: Graduates, undergraduates, postgraduates, researchers, and A/L students This internship programme offers flexible durations of two weeks, four weeks, and six weeks. Internships are available year-round, subject to space availability, and can be customised to meet specific requirements. Programme Overview: The internship provides comprehensive training in DNA fingerprinting for forensic and kinship testing, genetic disease diagnostics, GMO testing as well as many other widely used molecular applications. Two-Week Programme – LKR 48,000.00 Laboratory exposure working alongside our scientists in areas such as molecular forensics, kinship testing, GMO testing, and genetic disease diagnostics. Hands-on experience in molecular techniques by carrying out selected test methods. Four-Week Programme – LKR 72,000.00 Includes all components of the two-week programme, with the added opportunity to conduct a short-term research project. This project focuses on applying DNA fingerprinting techniques, involving a literature review, independent lab work, and data analysis. Six-Week Programme – LKR 96,000.00 Extends the four-week programme, allowing for a more in-depth research experience, with additional time for experimental work, data interpretation, and presentation of findings. Upon successful completion of the programme, interns will receive a certification letter detailing their training and experience. View FAQs Contact us If you are interested in doing an internship at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form
- Courses and Internships | Genetech
Courses and Internships Our vision and mission Our teaching facility is designed and organised with Dr. Maya Gunasekera’s original vision in mind, which is “anyone interested in this subject should be given the opportunity to learn it”. Therefore, we offer training programmes aimed at providing a comprehensive knowledge of basics to advanced molecular biology. This includes coursework and well-structured practical training in laboratory methods in molecular biology under the guidance of practicing scientists. Genetech School of Gene Technology offers training programmes in areas including disease diagnostic methods of molecular medicine for medical officers, forensic DNA typing for medico-legal personnel, laboratory management for technical officers and courses on gene technology for post-Advanced Level, undergraduate and graduate level students. View FAQs A large number of undergraduate and graduate level students have undergone training at Genetech as interns and research students. At present, research students and technicians that trained at Genetech are contributing immensely to the field of Molecular Diagnostics through various organisations islandwide. Internships We offer internship opportunities for local and foreign students who wish to work in an active molecular life science facility and obtain hands-on experience in a wide range of molecular biology techniques. Furthermore, our interns will be supervised by experienced scientists to actively engage in some short-term research and devise innovative solutions to complex challenges in this field. By choosing to do an internship at Genetech, you will avail yourself of an opportunity to work in a scientific environment which is quite unique in Sri Lanka. You will be able to work alongside scientists who are amongst the most experienced personnel in the molecular life sciences and learn in an environment that is fast-paced and exciting. Being a testing laboratory, Genetech is constantly working against time to deliver molecular biology-based testing services. Being a research institute, Genetech is always keen to branch out into new areas. Being a training organisation, Genetech can provide you with an opportunity to learn from practicing scientists and be mentored by experienced teachers whilst conducting research in a well-equipped facility. Courses The objective of these courses is to give all our students a comprehensive understanding of the essential principles of the subject. It aims to give each category of students a degree of knowledge and skill which would help meet the requirements of institutes of higher education and research anywhere in the world, and also help to accelerate the career development of personnel requiring a non-professional level of skill in molecular biology, such as medical and medico-legal personnel. View our internships 5 Day Practical Training Programme for A Level Students Advanced Certificate Course in DNA Fingerprinting Industry Based Training Programme Laboratory Practical Courses for A/L Students and Teachers Polymerase Chain Reaction (PCR) Technology Molecular Diagnostics of Infectious Diseases Certificate Course in Gene Technology If you are interested in doing an internship or course at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form
- Journal Publications - Page 2 | Genetech
Sathkumara, H. D., Merritt, A. J., Corea, E. M., Krishnananthasivam, S., Natesan, M., Inglis, T. J. J. & De Silva, A. D. (2018) Clinical, Bacteriologic, and Geographic Stratification of Melioidosis Emerges from the Sri Lankan National Surveillance Program. Am J Trop Med Hyg . 98(2), 607-615. Available from: doi: 10.4269/ajtmh.17-0441 Grifoni, A., Weiskopf, D., Arlehamn, C. S. L., Angelo, M., Leary, S., Sidney, J., Frazier, A., Phillips, E., Mallal, S., Mack, S. J., Tippalagama, R., Goonewardana, S., Premawansa, S., Premawansa, G., Wijewickrama, A., De Silva, A. D. & Sette, A. (2018) Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 714 adults from Colombo, Sri Lanka. Hum Immunol . 79(2), 87-88. Available from: doi: 10.1016/j.humimm.2017.12.007 Patil, V. S., Madrigal, A., Schmiedel, B. J., Clarke, J., O'Rourke, P., de Silva, A. D., Harris, E., Peters, B., Seumois, G., Weiskopf, D., Sette, A. & Vijayanand, P. (2018) Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis. Sci Immunol . 3(19). Available from: doi: 10.1126/sciimmunol.aan8664 Nanayakkara, K. K., Rodrigo, U. G., Perera, K. L. N. & Nanayakkara, C. D. (2017) Pre-natal diagnosis of thalassaemia in Sri Lanka: A ten year review. J Obstet Gynaecol . 37(7), 861-863. Available from: doi: 10.1080/01443615.2017.1306841 de Silva, W.S.I., Perera, M.M.N., Perera, K.L.N.S., Wickramasuriya, & A.M., Jayasekera G.A.U. (2017) In silico Analysis of osr40c1 Promoter Sequence Isolated from Indica Variety Pokkali. Rice Science, Vol. 24 (4): 228-234 Available from: doi: 10.1016/j.rsci.2016.11.002 . Gunasekara, J.M.A., Jayasekera, G.A.U, Perera, K.L.N.S. & Wickramasuriya, A.M, (2017) Development of a Sri Lankan rice variety Bg 94-1 harbouring cry2A gene of Bacillus thuringiensis resistant to rice leaffolder [Cnaphalocrocis medinalis (Guenée)]. Journal of the National Science Foundation of Sri Lanka, 45(2): 143–157. Available from: doi: 10.4038/jnsfsr.v45i2.8180 Goonawardhana, N.D.S., Jayasekara, G.S.K.W., Elanahai, V., Udagama, P.V., & Fernandopulle N.D. (2017) Population genetic data for ten miniSTR loci in the Sri Lankan population. International Journal of Legal Medicine. 131(4):969-970. Available from: doi: 10.1007/s00414-016-1512-3 Tian, Y., Babor, M., Lane, J., Schulten, V., Patil, V. S., Seumois, G., Rosales, S. L., Fu, Z., Picarda, G., Burel, J., Zapardiel-Gonzalo, J., Tennekoon, R. N., De Silva, A. D., Premawansa, S., Premawansa, G., Wijewickrama, A., Greenbaum, J. A., Vijayanand, P., Weiskopf, D., Sette, A. & Peters, B. (2017) Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA. Nat Commun. 8(1), 1473. Available from: doi: 10.1038/s41467-017-01728-5 Grifoni, A., Angelo, M. A., Lopez, B., O'Rourke, P. H., Sidney, J., Cerpas, C., Balmaseda, A., Silveira. C. G. T., Maestri, A., Costa, P. R., Durbin, A. P., Diehl, S. A., Phillips, E., Mallal, S., De Silva, A. D., Nchinda, G., Nkenfou, C., Collins, M. H., de Silva, A. M., Lim, M. Q., Macary, P. A., Tatullo, F., Solomon, T., Satchidanandam, V., Desai, A., Ravi, V., Coloma, J., Turtle, L., Rivino, L., Kallas, E. G., Peters, B., Harris, E., Sette, A. & Weiskopf, D. (2017) Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas. Front Immunol. Available from: doi: 10.3389/fimmu.2017.01309 Grifoni, A., Pham, J., Sidney, J., O'Rourke, P. H., Paul, S., Peters, B., Martini, S. R., de Silva, A. D., Ricciardi, M. J., Magnani, D. M., Silveira, C. G. T., Maestri, A., Costa, P. R., de-Oliveira-Pinto, L. M., de Azeredo, E. L., Damasco, P. V., Phillips, E., Mallal, S., de Silva, A. M., Collins, M., Durbin, A., Diehl, S. A., Cerpas, C., Balmaseda, A., Kuan, G., Coloma, J., Harris, E., Crowe Jr, J. E., Stone, M., Norris, P. J., Busch, M., Vivanco-Cid, H., Cox, J., Graham, B. S., Ledgerwood, J. E., Turtle, L., Solomon, T., Kallas, E. G., Watkins, D. I., Weiskopf, D. & Sette, A. (2017) Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans. J Virol. 91(24). Available from: doi: 10.1128/JVI.01469-17 Uehara, A., Tissera, H. A., Bodinayake, C. K., Amarasinghe, A., Nagahawatte, A., Tillekeratne, L. G., Cui, J., Reller, M. E., Palihawadana, P., Gunasena, S., De Silva, A. D., Wilder-Smith, A., Gubler, D. J., Woods, C. W. & Sessions, O. M. (2017) Analysis of Dengue Serotype 4 in Sri Lanka during the 2012-2013 Dengue Epidemic. Am J Trop Med Hyg. 97(1), 130-136. Available from: doi: 10.4269/ajtmh.16-0540 Krishnananthasivam, S., Jayathilaka, N., Sathkumara, H. D., Corea, E., Natesan, M. & De Silva, A. D. (2017) Host gene expression analysis in Sri Lankan melioidosis patients. PLoSNegl Trop Dis . 11(6). Available from: doi: 10.1371/journal.pntd.0005643 Krishnananthasivam, S., Sathkumara, H. D., Corea, E., Natesan, M. & De Silva, A. D. (2017) Gene Expression Profile of Human Cytokines in Response to Burkholderia pseudomallei Infection. mSphere . 2(2). Available from: doi: 10.1128/mSphere.00121-17 Grifoni, A., Angelo, M., Sidney, J., Paul, S., Peters, B., de Silva, A. D., Phillips, E., Mallal, S., Diehl, S. A., Botten, J., Boyson, J., Kirkpatrick, B. D., Whitehead, S. S., Durbin, A. P., Sette, A. & Weiskopf, D. (2017) Patterns of Cellular Immunity Associated with Experimental Infection with rDEN2Δ30 (Tonga/74) Support Its Suitability as a Human Dengue Virus Challenge Strain. J Virol . 91(8). Available from: doi: 10.1128/JVI.02133-16 Natesan, M., Corea, E., Krishnananthasivam, S., Sathkumara, H. D., Dankmeyer, J. L., Dyas, B. K., Amemiya, K., De Silva, A. D. & Ulrich, R. G. (2017) Calprotectin as a Biomarker for Melioidosis Disease Progression and Management. J Clin Microbiol. 55(4), 1205-1210. Available from: doi: 10.1128/JCM.02284-16 Angelo, M. A., Grifoni, A., O'Rourke, P. H., Sidney, J., Paul, S., Peters, B., De Silva, A. D., Phillips, E., Mallal, S., Diehl, S. A., Kirkpatrick, B. D., Whitehead, S. S., Durbin, A. P., Sette, A. & Weiskopf, D. (2016) Human CD4+ T cell responses to an attenuated tetravalent dengue vaccine parallel those induced by natural infection, in magnitude, HLA restriction and antigen specificity. J Virol . 91(5). Available from: doi: 10.1128/JVI.02147-16 Bodinayake, C. K., Tillekeratne, L. G., Nagahawatte, A., Devasiri, V., Kodikara Arachichi, W., Strouse, J. J., Sessions, O. M., Kurukulasooriya, R., Uehara, A., Howe, S., Ong, X. M., Tan, S., Chow, A., Tummalapalli, P., De Silva, A. D., Østbye, T., Woods, C. W., Gubler, D. J. & Reller, M. E. (2016) Emergence of Epidemic Dengue-1 Virus in the Southern Province of Sri Lanka. PLoS Negl Trop Dis. 10(10). Available from: doi: 10.1371/journal.pntd.0004995 Kamaral, L. C. J., Dassanayaka, P. N., Perera, K. L. N. S. & Perera, S. A. C. N. (2016) SSR markers reveal the population structure of Sri Lankan yellow dwarf coconuts (Cocos nucifera L.). Tree Genetics & Genomes 12, 116. Available from: doi: 10.1007/s11295-016-1076-x Kirupananthan, R., Kamaral, L. C. J., Galhena, G. H., Perera, K. L. N. S. & Magamage, M. P. S. (2016) Address the public health and food security concerns of babesiosis through molecular detection of Babesia bovis in suspected carrier cattle of selected localities in Sri Lanka. Procedia Food Science 6: 213-219. Available from: doi: 10.1016/j.profoo.2016.02.053 Weiskopf, D., Angelo, M. A., Grifoni, A., O'Rourke, P. H., Sidney, J., Paul, S., De Silva, A. D., Phillips, E., Mallal, S., Premawansa, S., Premawansa, G., Wijewickrama, A., Peters, B. & Sette, A. (2016) HLA-DRB1 Alleles Are Associated With Different Magnitudes of Dengue Virus-Specific CD4+ T-Cell Responses. J Infect Dis. 214(7), 1117-1124. Available from: doi: 10.1093/infdis/jiw309 de Alwis, R., Bangs, D. J., Angelo, M. A., Cerpas, C., Fernando, A., Sidney, J., Peters, B., Gresh, L., Balmaseda, A., de Silva, A. D., Harris, E., Sette, A. & Weiskopf, D. (2016) Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype. J Virol. 90(9), 4771-4779. Available from: doi: 10.1128/JVI.02892-15 Olsen, A., Chen, Y., Ji, Q., Zhu, G., De Silva, A. D., Vilchèze, C., Weisbrod, T., Li, W., Xu, J., Larsen, M., Zhang, J., Porcelli, S. A., Jacobs Jr, W. R. & Chan, J. (2016) Targeting Mycobacterium tuberculosis Tumor Necrosis Factor Alpha-Downregulating Genes for the Development of Antituberculous Vaccines. MBio. 7(3). Available from: doi: 10.1128/mBio.01023-15 Tissera, H., Amarasinghe, A., Gunasena, S., De Silva, A. D., Yee, L. W., Sessions, O., Muthukuda, C., Palihawadana, P., Lohr, W., Byass, P., Gubler, D. J. & Wilder-Smith, A. (2016) Laboratory-Enhanced Dengue Sentinel Surveillance in Colombo District, Sri Lanka: 2012-2014. PLoS Negl Trop Dis. 10(2). Available from: doi: 10.1371/journal.pntd.0004477 Weiskopf, D., Angelo, M., Zapardiel, J., Seumois, G., De Silva, A., De Silva, A. D., Vijay, P., Peters, B. & Sette, A. (2016) DENV-specific CD4 T-cells dominantly recognize capsid-derived epitopes and display a cytotoxic phenotype. J Immunol . 196 (1). Available from: https://www.jimmunol.org/content/196/1_Supplement/147.13/tab-article-info Padumadasa, C., Perera, K. L. N. & Sankalpani, E. M. N. (2016) DNA intercalation and cleavage studies of plumbagin and phenanthroline-based Cu(II) complex, [Cu(PLN)(PHEN)]NO3. Int J Chem Stud. 4(4), 87-90. Available from: https://www.chemijournal.com/archives/?year=2016&vol=4&issue=4&ArticleId=282&si=false Fernando, A. N., Malavige, G. N., Perera, K. L. N., Premawansa, S., Ogg, G. S. & De Silva, A. D. (2015) Polymorphisms of Transporter Associated with Antigen Presentation, Tumor Necrosis Factor-α and Interleukin-10 and their Implications for Protection and Susceptibility to Severe Forms of Dengue Fever in Patients in Sri Lanka. Journal of Global Infectious Diseases. 7(4): 157–164. Available from: doi: 10.4103/0974-777X.170501 Weiskopf, D., Cerpas, C., Angelo, M. A., Bangs, D. J., Sidney, J., Paul, S., Peters, B., Sanches, F. P., Silvera, C. G., Costa, P. R., Kallas, E. G., Gresh, L., de Silva, A. D., Balmaseda, A., Harris, E. & Sette, A. (2015) The Human CD8+ T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets. J Infect Dis . 212(11), 1743-1751. Available from: doi: 10.1093/infdis/jiv289 Page 2 of 3 Journal Publications 1 2 3
- Oligonucleotide and Gene synthesis | Genetech
Oligonucleotide and Gene synthesis We offer primer synthesis services covering different concentration scales from 0.025 to 1µmole. Different purification options using techniques such as desalt, MOPC, HPLC and PAGE are available as per requirement of the customer. We also offer primer modifications such as fluorescent labelling, non-fluorescent modifications, dark quenchers and internal modifications. Oligonucleotide/Primer synthesis Gene synthesis We offer customised gene synthesis services in a plasmid DNA state with a free cloning service, as well as free DNA sequencing to confirm the sequence of the gene. Our customised gene synthesis service offers to generate genes based on the sequence requirement of the customer. With our free cloning service, the synthesised gene is made available in a plasmid DNA state. Our free sequencing service guarantees 100% sequence accuracy. Contact us
- Our Services | Genetech
Our Services Molecular Diagnostics Sex Determination of Birds DNA Sequencing Product Development DNA Typing Animal Testing Oligonucleotide and Gene synthesis Student Projects GM and Other Food Testing Courses & Internships Customised Biotechnology Solutions Collaborative Research
- Our Tests | Genetech
Our Tests Molecular Diagnostics We pioneered the use of molecular diagnostics in Sri Lanka. We seek evidence of a disease at the basic causative level by detecting the nucleic acids based on PCR technology. Read More GM and Other Food Testing We use a PCR method to identify the most common genetic elements that are generally found in Genetically Modified (GM) crops. Our test can be applied to a wide range of food items including crops and processed food. Read More DNA Typing We pioneered the use of DNA typing for human identification for forensic casework and analysis of family relationships including parentage testing. Read More Sex Determination of Birds Many bird species are monomorphic; thus, males and females cannot be distinguished visually. We offer molecular sexing for proper gender assignment of a wide range of bird species with an accuracy of 99.9%. Read More Animal Testing We are the only firm to provide a PCR based animal disease testing service in Sri Lanka. We offer tests which detect Canine Parvovirus, Canine Distemper, Canine Babesiosis and Canine Ehrlichiosis. In addition to animal disease testing, we provide a cattle parentage testing service through the use of DNA typing. Read More