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  • Molecular Biology Courses | Genetech | Colombo

    Our Firm Genetech is a multi-faceted institution and our activities can be broadly categorised into the following areas: ​ Molecular disease diagnostics DNA typing for paternity testing and forensic casework Teaching of basic to advanced molecular biology Training of personnel involved in molecular biology Genetically modified (GM) and other food testing Sex determination of birds Diagnostics of animal diseases Research in the molecular life sciences Customised biotechnology solutions Molecular biology products Read our story View our services One day workshop on gene technology Introductory lecture on "Introduction to gene technology and its current applications" Theory and hands-on practical session covering: DNA extraction PCR (Polymerase Chain Reaction) Gel Electrophoresis Basics in DNA profiling, DNA fingerprinting and DNA typing Basics in applications of PCR in disease diagnosis This workshop is well-suited for all local and international A/L students. Fee: Rs. 5,850 per person (Minimum 10 students per session) Please contact us to book a date. VIEW MORE COURSES Certificate course in gene technology 10-day course Classes on two consecutive weekdays over a 5 week period Course Fee: Practicals - Rs. 50,000 Lectures - Rs. 30,000 LEARN MORE Short-term internships for students These internships are ideal for students who are undertaking AS/A2 exams or pursuing an undergraduate degree and looking for industrial exposure in gene technology. ​​ Duration: 2-6 weeks ​ LEARN MORE Long term internships and research opportunities 6 weeks and upwards Customised individual programmes available CONTACT US Our Leadership Our leaders at Genetech set the policies and the strategic direction of the firm. Collaborating with each other, their knowledge and experience come together to make a positive impact for all our stakeholders - students, patients, healthcare providers and local and global communities. Dr. Maya Gunasekera Founder of Genetech (1961 - 2006) View Profile The working culture is built by leaders who believe empathy is absolutely vital. This is demonstrated by talking and listening to people, understanding what they care about, adapting to their needs and catering to what they want. Dhammika Gunasekera Owner of Genetech and Managing Trustee of Genetech Research Institute View Profile Dr. Nandika Perera Head of Forensic DNA Typing and Parentage Testing View Profile Samudi Mohotti Senior Scientist View Profile Our Values Positivity Our commitment to sustain a positive environment for our employees as well as our clients is one of the key factors that sets us apart from our competitors Collaboration Collaboration is at the core of everything we do. We enjoy interacting with various types of people whilst appreciating the cultural diversity that they bring to the community. Excellence Delivering excellence has always been our main focus as we love inspiring and elevating the communities we touch. Integrity We always act with integrity, and we have strong moral and ethical principles to be followed at all times regardless of the consequences. Read more

  • Molecular Diagnostics | Genetech

    Molecular Diagnostics Did you know? We pioneered the use of molecular diagnostics in Sri Lanka. This field, which was almost unknown to the medical fraternity in Sri Lanka is now widely used in delivering high quality patient management. Molecular diagnostics is now an accepted and even essential part of the health care system since it was introduced to Sri Lanka by us in 2002. How we strengthened our clients' trust In order to standardise our tests and strengthen our clients' trust, We have applied for and obtained ISO 15189 accreditation. Thus, our tests including those related to molecular disease diagnostics are excellent in all aspects. The importance of nucleic acids Infectious diseases are caused by a wide variety of organisms, ranging from multi-cellular parasites and fungi to uni-cellular bacteria to non-cellular viruses. These organisms cover a wide range of phyla, and have extremely diverse ways of infecting human beings. In spite of these differences, they all possess nucleic acids (DNA or RNA molecules), their hereditary material. This DNA or RNA forms the basis of their individuality, and because it is the basis of diversity, it is possible to identify these organisms from their DNA or RNA. What we offer with PCR technology Unlike other diagnostic methods, which rely on microscopy, culture, biochemical characteristics and indirect antibody detection, molecular diagnostics seeks evidence of a disease at the very basic causative level by detecting the nucleic acids based on PCR (Polymerase Chain Reaction) technology. ​ This technology is also used to detect changes or mutations in our DNA, which can cause disease conditions known as genetic disorders. While some of these genetic disorders are passed from generation to generation, some happen spontaneously. Genetech offers DNA-based testing services for a wide variety of such genetic disorders and cancer markers. Contact us View Price List and Sample Collection Guide

  • DNA Typing | Genetech

    DNA Typing Our passion to improve We pioneered the use of DNA typing for human identification for forensic casework and analysis of family relationships including parentage testing. We are a major supplier of this technology to the medico-legal community and the judicial system in Sri Lanka. Our reputation for integrity and reliability has made us the main provider of forensic DNA testing in the country. Over 4000 cases of disputed parentage and another 4000 criminal cases have had the advantage of DNA evidence through Genetech. What is DNA typing? DNA typing is a method of identifying individuals from the differences in their DNA. It is used for forensic casework as well as for determining familial relationships between individuals including paternity, maternity and siblingship. Advantages of DNA typing The science of DNA typing relies on technology that allows an individual's DNA to be examined and analysed. A person's DNA is unique: no two individuals (with the exception of identical twins) have the same DNA. Every cell in a person's body has the same DNA. Hence, DNA taken from any part of the body from the same individual will always be the same. DNA typing can be performed from many types of biological specimens including blood, saliva, sperm cells, muscle, teeth and bones. Thus, a person's DNA can be typed from very little tissue or body fluid. DNA typing is used for two major purposes: Identification of individuals from biological samples: This is mainly done in forensic casework, where it is possible to determine the identity of a criminal by typing the DNA left behind at the scene of the crime. Determination of familial relationships: This includes paternity testing, maternity testing, sibling testing, grand-parent testing, and even the identification of mutilated bodies. DNA typing is the best method of identifying individuals and determining familial relationships due to many reasons. It is extremely sensitive: with even a very small amount of tissue, the test can be performed successfully. It is also very accurate: it can give a test result with a very high degree of certainty. It is very reliable: the likelihood of obtaining a false result can be minimised, and the likelihood of making an error in the conclusion can be calculated. How does DNA typing work? In the DNA typing process, a DNA banding pattern or profile of an individual is first obtained from a tissue sample. The DNA profile is observed in the form of a set of DNA bands known as alleles. Each person has a maximum of two specific alleles for a given genetic location. This DNA profile is compared with the profile obtained from a sample taken from the scene of a crime. If the alleles in the two profiles match, then it can be said that the sample taken from the scene of the crime is from the individual that was tested. DNA typing services Child custody and maintenance: In cases where one parent is claiming the custody and maintenance of a child and the other parent is refusing to accept parentage. Proof of adultery: Especially in divorce cases where the paternity of the child is suspect, and the wife is being accused of adultery, DNA typing can be used to determine whether the husband is the father of the child. View all Cost We are happy to announce that after much research and optimisation, we have streamlined our DNA typing methods, and we are therefore able to provide DNA typing services at a reasonable cost. We perform the same DNA typing tests which are used by internationally recognised laboratories, and maintain the same standards of quality so that the conclusions made by us can be verified by any accredited forensic DNA typing laboratory in the world. Contact us View Price List Quality control DNA typing is a highly specialised procedure which requires knowledge and skill. Furthermore, for DNA typing evidence to be acceptable in a Court of Law, it has to meet certain quality standards, which have been well documented and followed by forensic DNA laboratories worldwide. Accordingly in 2010, we became the first DNA typing laboratory in Sri Lanka to achieve ISO 15189:2007 (now 15189:2012) accreditation from Sri Lanka Accreditation Board (SLAB). Read more Accuracy of evidence DNA testing is the most accurate and reliable means of identity verification and parentage testing. The degree of accuracy of the test will depend on the genetic diversity of the Sri Lankan population as well as the number of genetic locations (STR loci) which are tested. There is no mandatory number of STR loci required for a test, but the testing of nine STR loci or more is generally considered to be sufficiently accurate. We test up to 15 STR loci. Read more Ethical Guidelines DNA typing is performed ethically only with the informed consent of the individual whose DNA is being typed. The persons concerned will be informed about the consequences of the test. Where such consent cannot be given such as in the case of minors, the consent of the guardian has to be obtained. We will not undertake samples for parentage testing without written consent from all living parties who will be tested. Read more Please contact us for personalised support on parentage and testing of other family relationships.

  • GM and Other Food Testing | Genetech

    Genetically Modified and Other Food Testing Definition Genetically modified (GM) foods are foods derived from organisms whose genetic material (DNA) has been modified through the introduction of a gene from a different organism. Currently available GM foods stem mostly from plants. What we do We use a PCR method to identify the most common genetic elements that are generally found in GM crops. The test is very sensitive and able to detect 0.1% GM content. In addition to the common genetic elements, on request, we also offer to detect other genetic elements that are assumed to have been integrated into the plants during the GM procedure. Our test can be applied to crops such as corn, soy, canola, and potato as well as processed food items such as tea, desiccated coconut, bakery & confectionery items, breakfast cereals & snacks, food additives, and others. Validation of method The test method has been validated according to the guidelines given by the European Commission Joint Research Centre for food samples and uses positive (European Certified reference materials) and negative control samples in order to assure the best qualitative results. Who we help Our testing facility has been utilised by the Food Control Administration Unit, Ministry of Health, Sri Lanka for the screening of imported seeds and food products as well as local farmers, manufactures and exporters to certify their products are free from GM food materials. Contact us View price list

  • Animal Testing | Genetech

    Animal Testing What is Parvovirus and why is early diagnosis essential? Canine Parvovirus (CPV) is a highly contagious pathogen primarily affecting dogs. This virus can also infect other mammals including cats. If untreated, the risk of death may be high. Thus, a rapid and early diagnosis could save their lives. ​ Detection of the virus can help you select an appropriate treatment regimen for your animals, prevent the spread of the virus and save them from secondary infections. Why we recommend a PCR test over an ELISA test The sensitivity of an ELISA test depends on the Ag/Ab concentration and the availability. Thus, it could lead to false positive or negative results. In contrast, our PCR (Polymerase Chain Reaction) test detects the viral genome and produces no false positive or negative results. This is because it is dependent on the availability of the virus but not its products or Abs. The positive result of an ELISA test can be caused by organisms other than the target. On the other hand, our PCR test detects genetic sequences unique to the target pathogen. Therefore, its specificity is much higher than an ELISA test. The accuracy of the ELISA test varies, and it depends on the Ag/Ab availability. Our PCR test offers a consistent accuracy of 99%. What is tick fever and why may early detection be crucial? Tick fever is a common canine disease in Sri Lanka which is caused through the bite of an infected tick carrying an insidious and deadly organism. Scientifically, it is known as Canine Ehrlichiosis and Canine Babesiosis. ​ Early detection may prevent the dog from experiencing severe anemic conditions caused by the disease due to the highly pathogenic nature of it. Furthermore, the specific detection will help choose a suitable treatment regimen for your dog. Why microscopy and antibody tests are not ideal Some stages of the parasite life cycle cannot be observed through the microscope. Therefore, the probability of obtaining false results is high. It takes several days to develop antibodies against a certain infection in the body. Hence, it is difficult to diagnose the infection early. Antibodies may be present in the body even after the disease is cured. Thus, if the test is done after the infection is cured, the result may be false positive. What we offer We are the first firm to provide a PCR based animal disease testing service in Sri Lanka. We offer tests which detect Canine Parvovirus, Canine Distemper, Canine Babesiosis and Canine Ehrlichiosis. In addition to animal disease testing, we provide a cattle parentage testing service through the use of DNA typing. Contact us View price list

  • Sex Determination of Birds | Genetech

    Sex Determination of Birds Purpose Sex determination of birds is required for many purposes including bird breeding and conservation programmes. Why we test Many bird species are monomorphic; thus, males and females cannot be distinguished visually due to their similar phenotypic traits. On the other hand, sexually dimorphic bird species often do not display distinct visual features, characteristics or behavioural traits until they reach adult stage, thereby preventing the identification of gender in younger individuals. What we offer We offer molecular sexing for proper gender assignment of a wide range of bird species with an accuracy of 99.9%. Our method uses bird feathers to conduct a non-invasive, rapid, efficient and cost-effective sex determination. If available, other bird tissue samples including blood can be used for the test. ​ Contact us View Price List

  • Certificate Course | Genetech

    Certificate Course in Gene Technology (60 hours) Theory: ​ DNA, RNA structure and function Messenger RNA, Transfer RNA & proteins Chromosomes, genes, alleles, karyotypes, phenotype & genotype Extracting DNA from different sources Basic methods in bacteriology DNA modifying enzymes Genetic engineering & gene splicing Electrophoresis & quantification of DNA Polymerase chain reaction DNA fingerprinting in forensic casework Biotechnology in medicine & industry ​ Practicals (hands-on practical experience on an individual basis for each student): ​ ​ Laboratory rules & safety precautions Use of micropipettes Preparation of reagents Plating & quantifying of bacteria Forensic DNA testing: Extraction of DNA, PCR & gel electrophoresis Isolation of plasmid DNA Spectrophotometric determination of DNA DNA sequence data analysis ​ Course Fee: Practicals: Rs. 50,000 Lectures: Rs. 30,000 View FAQs Contact us If you are interested in doing this course at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form

  • DNA Sequencing | Genetech

    DNA Sequencing Genetech is an authorised agent for a world-leading company of genomic analysis which provides a wide variety of services including DNA sequencing and oligo nucleotide synthesis. This has enabled Genetech to provide the following services to Sri Lanka at an affordable price range. DNA Sequencing services Capillary Electrophoresis Sequencing CES analyses DNA sequences using Big Dye chemistry (Sanger Sequencing) and the ABI 3730xl analyser. CES can be performed either in individual PCR tubes or in 96 well plates for high throughput sequencing. The reaction can be conducted using both universal as well as custom made primers. The method is commonly used to sequence relatively shorter fragments of DNA for a variety of purposes. Sequencing of PCR products and plasmid CES is generally used for sequencing of PCR products and plasmid DNA up to 1,000 bp in length. A special CES service is also available for the ‘difficult sequencing’ such as high GC rich DNA, homopolymers, repetitive sequences and those with strong secondary structures. ​ In addition, we accept the unamplified DNA and unprocessed biological samples for sequencing services. We also undertake to sequence PCR products containing nonspecific bands. Upon request, post sequence analysis (sequence alignments, phylogenetic tree construction, genome annotation etc.) services are also available to help the researchers interpret the results. Sequencing bacterial and fungal colonies 16S r-RNA gene sequencing is a common method used to identify bacterial species. As per the customer requirement, we undertake to sequence different length options up to 1400 bp. For the sequencing of fungal colonies, we provide three options: 18S rRNA gene (> 1,600 bp guaranteed), 26S rRNA gene (> 1,300 bp guaranteed) and ITS region (> 500 bp guaranteed). We also offer post-sequencing analysis services to assist species identification. Next-Generation Sequencing NGS, massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has been developed for genomic research during recent years. The technology performs parallel sequencing of millions of DNA fragments which are assembled into single genome using bioinformatics analysis. In contrast to the first-generation Sanger sequencing technology, NGS provides a much more efficient tool enabling the sequencing of the entire human genome within a single day. ​ We offer numerous NGS sequencing techniques such as Whole Genome Sequencing, Metagenome Sequencing, Exome Sequencing, Transcriptome Sequencing and Epigenome Sequencing. Different NGS platforms are available to meet the varying requirement of these techniques. Our scientists will help you choose the best NGS option and platforms depending on your requirement. We also offer to assist in the bioinformatics analysis of NGS data. Contact us

  • CONTACT US | Genetech

    54 Kitulwatte Road, Colombo 08, Sri Lanka ​ +94 112696992 +94 11 2696881 Fax: +94 (0) 11 2686137 Email: info@genetechsrilanka.com Head of Forensics, Parentage Testing and DNA Typing: Dr. Nandika Perera Email: nandika@genetechsrilanka.com Head of the School of Gene Technology and Disease Diagnostics: Mrs. Vajirapani De Silva Email: vajirapani@genetechsrilanka.com Contact Form Name Email Subject Message Success! Message received. Send DNA Sequencing Services Email: sequencing.genetech@gmail.com

  • Diagnostics of Infectious Diseases | Genetech

    Molecular Diagnostics of Infectious Diseases This is a course which can be customised based on the request of degree awarding institutes, hospitals and groups of individuals such as lawyers, lecturers, scientists and teachers who wish to obtain a foundation in the theoretical and practical aspects of molecular diagnostics. ​ Course Content: ​ Molecular Diagnostic Tools Extraction of nucleic acids (DNA/RNA) from different clinical specimens Development of DNA probes and nucleic acid hybridization PCR (Polymerase Chain Reaction) PCR-Hybridization ​ View FAQs Contact us If you are interested in doing this course at Genetech, please submit the Inquiry Form below or email us at info@genetechsrilanka.com to receive further details. View Inquiry Form